Blink once and the NFL season is already in Week 3. Below is the complete Week 2 schedule, including the betting odds for each matchup.
To kick-off the slate, Michael Penix Jr. makes his season debut for the Atlanta Falcons on Thursday night against the Green Bay Packers in a game that both teams need for some confidence. While the Packers beat the New York Jets last week, a lot had to go right for them to pull off the overtime victory against a team they were heavily favored against.
On the other side, Atlanta lost 34-3 last week with Cooper Rush under center and they're hoping their former first-round pick can play at a much higher level.
The Denver Broncos and Los Angeles Rams close out the Sunday slate with a terrific Sunday night matchup in the Mile High between two teams that could meet again in February.
Finally, Week 3 concludes with a Philadelphia Eagles vs. Chicago Bears battle from Soldier Field, though Bears quarterback Caleb Williams is in doubt to play in that one after suffering a hamstring injury last week.
Falcons @ Packers (TNF)
Date: Thursday, September 24, 2026
Time: 8:15 PM ET
Location: Lambeau Field, Green Bay, WI
Betting Odds:
Spread | Total (O/U) | Money | |
+5.5 -110 | O 43.5 -105 | +220 | |
-5.5 -110 | U 43.5 -115 | -270 |
Panthers @ Browns
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: Huntington Bank Field, Cleveland, OH
Betting Odds:
Spread | Total (O/U) | Money | |
-2.5 -120 | O 42.5 -105 | -150 | |
+2.5 +100 | U 42.5 -115 | +125 |
Bengals @ Steelers
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: Acrisure Stadium, Pittsburgh, PA
Betting Odds:
Spread | Total (O/U) | Money | |
-3.5 -110 | O 42.5 -110 | -190 | |
+3.5 +110 | U 42.5 -110 | +160 |
Texans @ Colts
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: Lucas Oil Stadium, Indianapolis, IN
Betting Odds:
Spread | Total (O/U) | Money | |
-2.5 -115 | O 42.5 -110 | -150 | |
+2.5 -105 | U 42.5 -110 | +125 |
Chiefs @ Dolphins
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: Hard Rock Stadium, Miami Gardens, FL
Betting Odds:
Spread | Total (O/U) | Money | |
-11.5 -110 | O 46.5 -105 | -750 | |
+11.5 -110 | U 46.5 -115 | +525 |
Chargers @ Bills
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: Highmark Stadium, Orchard Park, NY
Betting Odds:
Spread | Total (O/U) | Money | |
+7.0 -105 | O 50.5 -105 | +280 | |
-7.0 -115 | U 50.5 -115 | -360 |
Patriots @ Jaguars
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: EverBank Stadium, Jacksonville, FL
Betting Odds:
Spread | Total (O/U) | Money | |
+3.0 -115 | O 45.5 -105 | +135 | |
-3.0 -105 | U 45.5 -115 | -160 |
Jets @ Lions
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: Ford Field, Detroit, MI
Betting Odds:
Spread | Total (O/U) | Money | |
+6.5 -105 | O 47.5 -105 | +255 | |
-6.5 -115 | U 47.5 -115 | -315 |
Seahawks @ Commanders
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: Northwest Stadium, Landover, MD
Betting Odds:
Spread | Total (O/U) | Money | |
-7.0 -110 | O 40.5 -105 | -310 | |
+7.0 -110 | U 40.5 -115 | +250 |
Titans @ Giants
Date: Sunday, September 27, 2026
Time: 1:00 PM ET
Location: MetLife Stadium, East Rutherford, NJ
Betting Odds:
Spread | Total (O/U) | Money | |
+2.5 +100 | O 39.5 -110 | +125 | |
-2.5 -120 | U 39.5 -110 | -150 |
Cardinals @ 49ers
Date: Sunday, September 27, 2026
Time: 4:05 PM ET
Location: Levi's Stadium, Santa Clara, CA
Betting Odds:
Spread | Total (O/U) | Money | |
+8.5 -110 | O 47.5 -115 | +350 | |
-8.5 -110 | U 47.5 -105 | -450 |
Vikings @ Buccaneers
Date: Sunday, September 27, 2026
Time: 4:05 PM ET
Location: Raymond James Stadium, Tampa, FL
Betting Odds:
Spread | Total (O/U) | Money | |
-1.5 -110 | O 42.5 -110 | -120 | |
+1.5 -110 | U 42.5 -110 | +100 |
Ravens vs. Cowboys (Brazil)
Date: Sunday, September 27, 2026
Time: 4:25 PM ET
Location: Maracana Stadium, Rio de Janeiro, BR
Betting Odds:
Spread | Total (O/U) | Money | |
-3.5 -105 | O 52.5 -110 | -180 | |
+3.5 -115 | U 52.5 -110 | +150 |
Raiders @ Saints
Date: Sunday, September 27, 2026
Time: 4:25 PM ET
Location: Caesars Superdome, New Orleans, LA
Betting Odds:
Spread | Total (O/U) | Money | |
+3.0 +100 | O 43.5 -120 | +150 | |
-3.0 -120 | U 43.5 +100 | -180 |
Rams @ Broncos (SNF)
Date: Sunday, September 27, 2026
Time: 8:20 PM ET
Location: Empower Field, Denver, CO
Betting Odds:
Spread | Total (O/U) | Money | |
-2.5 -115 | O 45.5 -110 | -140 | |
+2.5 -105 | U 45.5 -110 | +120 |
Eagles @ Bears (MNF)
Date: Monday, September 28, 2026
Time: 8:15 PM ET
Location: Soldier Field, Chicago, IL
Betting Odds:
Spread | Total (O/U) | Money | |
-4.5 -110 | O 41.5 -105 | -225 | |
+4.5 -110 | U 41.5 -115 | +185 |
All odds written in this article were correct at the time of writing and are subject to change.
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