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New Orleans Saints vs. Detroit Lions
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New Orleans Saints vs. Detroit Lions Preview & Betting Odds

The Saints travel North to Detroit in Week 1 of the NFL season to face the high-powered Lions offense.

Game

New Orleans Saints @ Detroit Lions

Date

Sunday, September 13, 2026

Time

1:00 p.m. ET / 12:00 p.m. CT

Stadium

Ford Field, Detroit, MI

TV Channel

FOX

Dan Campbell and the Detroit Lions are eager to kick off the 2026 season, after missing the playoffs in 2025 with a 9-8 record.

The Lions have gone all-in on Jahmyr Gibbs by signing one of the best running backs in the NFL to a three-year, $67.5 million contract this offseason. Detroit did, however, have to break up 'Sonic' and 'Knuckles' by trading David Montgomery to the Houston Texans.

The New Orleans Saints have kept their core intact, with quarterback Tyler Shough primed to start his first full season in the NFL after making his first start in Week 9 last year.

The Saints signed experienced running back Travis Etienne Jr. this offseason to complement Alvin Kamara and Chris Olave. Etienne has rushed for 1,000+ yards in three of his first four seasons in the NFL and will allow 31-year-old Kamara to focus on specific third-down packages.

The last time the two teams played each other was in 2023, when the Lions beat the Saints 33-28 in New Orleans. Jared Goff found his two top targets in that game, Sam LaPorta (140 yards) and Amon-Ra St. Brown (49 yards), for a combined 189 yards and two touchdowns. Derek Carr was the quarterback for New Orleans, and Taysom Hill was the team's leading rusher with 59 yards on 13 carries.

The Saints secondary will have their hands full with this high-powered Detroit offense, especially Kool-Aid McKinstry, who will likely be tasked with covering St. Brown.

Saints vs. Lions Preview & Betting Odds

All odds written in this article were correct at the time of writing and are subject to change.

Spread, Total, Money

Spread

Total

Money

NO Saints

+6.5 +105

O 49.5 -115

+265

DET Lions

-6.5 -125

U 49.5 -105

-330

Odds presented by bet365

Touchdown Scorer Odds

First TD

Anytime TD

Jahmyr Gibbs

+235

-290

Amon-Ra St. Brown

+600

+105

Travis Etienne

+625

+115

Chris Olave

+900

+165

Jameson Williams

+950

+170

Sam LaPorta

+1100

+195

Juwan Johnson

+1500

+265

Jacob Saylors

+1650

+290

Devaughn Vele

+1650

+310

Isaac TeSlaa

+2000

+375

Tyler Shough

+2000

+350

Bryce Lance

+3000

+575

Jahmyr Gibbs Rushing Props

Over

Under

84.5 Rushing Yards

-115

-115

18.5 Rushing Attempts

-125

-105

17.5 Yard Longest Rush

-115

-115

100+ Rushing Yards

+170

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