Craig Bellamy takes his Wales side to Lisbon where they will meet Portugal in the UEFA Nations League.
The Dragons compete in League A for the second time after topping a League B group containing Turkey, Iceland and Montenegro in 2024/25 and now face three nations that sit among the top 25 in FIFA's World Rankings.
Norway and Denmark occupy 19th and 21st respectively, but first up is the seventh-best team in the world Portugal.
Under new management following Roberto Martinez's departure over the summer, veteran coach Jorge Jesus has selected an incredibly talented 25-man squad to begin their defence of the Nations League title.
As expected, a good majority of the discourse surrounding Jesus' first squad has been centred around all-time top goalscorer Cristiano Ronaldo. The 41-year-old was rumoured to be retiring from international duty at the World Cup, however, remains part of the squad as he aims to become the first player in history to reach professional 1000 goals.
With just one uncapped player named among the squad, Jesus has selected many of the same names that failed to go beyond the last 16 in North America; defeated by eventual winners Spain. Paris Saint-Germain trio Nuno Mendes, Vitinha and Joao Neves all make the squad, as well as stalwarts Bruno Fernandes and Ruben Dias. Elsewhere from the Premier League, Diogo Dalot and Pedro Neto also earn call-ups.
Benfica goalkeeper Samuel Soares could make his senior debut after impressing for the youth teams, but he will have to displace mainstay Diogo Costa between the sticks.
Soares replaces Wolves 'keeper Jose Sa, with his club's relegation to the Championship seemingly costing him his place in the national team setup. Manchester City's Matheus Nunes also misses out alongside Tottenham's expensive summer signing Mateus Fernandes, who drops to the U21s.
Selecao defeated Spain on penalties to claim their second Nations League title in 2025 and are 8/1 to seal a hat-trick of successes.
After facing Wales in their opener, Portugal face back-to-back away matches against Norway and Denmark before heading back to Lisbon where they will face-off against Norway for the second time in little over a week.
Portugal squad to face Wales, Denmark & Norway
Goalkeepers: Diogo Costa, Rui Silva, Samuel Soares
Defenders: Joao Cancelo, Diogo Dalot, Ruben Dias, Tomas Araujo, Renato Veiga, Goncalo Inacio, Nuno Mendes, Nuno Tavares
Midfielders: Joao Palhinha, Ruben Nves, Vitinha, Joao Neves, Bernardo Silva, Bruno Fernandes
Forwards: Francisco Conceicao, Franciso Trincao, Rafael Leao, Pedro Neto, Joao Felix, Cristiano Ronaldo, Goncalo Ramos, Fabio Silva
Any odds displayed were correct at the time of writing and are subject to fluctuation.
