Uruguay will be searching for their first win of the 2026 World Cup campaign when locking horns with Group H leaders Spain in the early hours of Saturday morning.
A difficult start to the tournament saw Marcelo Bielsa's side held to a 1-1 draw by Saudi Arabia, and their woes were worsened when managing just a point against World Cup debutants Cape Verde.
Spain are all but through to the Round of 32 -- irrespective of the result against Uruguay -- but victory in Mexico would see them top the group standings with seven points.
The Estadio Guadalajara clash will mark the first time that Uruguay and Spain have locked horns since 2013, where La Roja emerged as 2-1 winners in the FIFA Confederations Cup via goals from Pedro and Roberto Soldado.
Uruguay v Spain Player of the Match Odds
(Odds will display when market is available)
Lamine Yamal marked his return to the starting XI with a goal as Spain cruised to a 4-0 win over Saudi Arabia last time out, and he's priced as the favourite to win the Player of the Match award against Uruguay.
The Barcelona sensation has scored seven goals in 27 appearances for the national team -- one of which came in Spain's 2022 Euros-winning campaign -- and he features prominently in the betting to win the World Cup Golden Ball, despite only featuring as a substitute in Spain's goalless draw to Cape Verde in their opening match.
Mikel Oyarzabal was named Player of the Match for a stellar performance against Saudi Arabia last time out -- where he scored twice and registered one assist -- and he's priced at 7/4 to be the standout player once again.
Uruguay star Federico Valverde is yet to show what he is made of at the 2026 World Cup, but if anyone is capable of unlocking the Spain back line to lead La Celeste to glory in Mexico, you'd back it to be him.
Uruguay have had very little luck from their centre forward department thus far -- with their only goals coming from wide men Maximiliano Araujo and Agustin Canobbio -- but striker Federico Vinas is available at 4/1 to win the Player of the Match award.
All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
