Struggling Manchester United host Aston Villa in the Premier League on Sunday afternoon.
The Red Devils have had their worst ever start to a Premier League season, earning just seven points from their first nine matches to sit 17th in the table.
Should they fall to defeat against the Villans, Michael Carrick's side will likely find themselves in the relegation zone for the upcoming international break, leaving his future increasingly uncertain.
Meanwhile, Aston Villa continue to have teething issues in their rebuild, having failed to win any of their last three in all competitions, with a 1-1 draw against Fulham their latest result in the Premier League.
Despite this, the Villans are currently on a run of five without defeat in their domestic league and recently defeated Manchester City 2-1 at Villa Park.
Michael Carrick looks set to be boosted by the returns of Patrick Dorgu and Marcus Rashford from injury, though both are likely to be introduced from the bench.
Carlos Baleba is likely to miss the weekend's fixture, having pulled up in the midweek win over Roma, while Lisandro Martinez will serve his one-match suspension, having been sent off against Chelsea last time out.
Martinez's absence is likely to see Ayden Heaven partner Harry Maguire at the back, with Leny Yoro and Diogo Dalot continuing as make-shift full backs.
Andrey Santos is likely to come in for Carlos Baleba to partner former Villa man Youri Tielemans in midfield, behind a trio of Matheus Cunha, Bruno Fernandes and Amad Diallo. Brian Mbeumo should continue up front in Benjamin Sesko's continued absence.
For Aston Villa, Matty Cash will miss the trip to Manchester - having received his fifth yellow card of the season in the draw against Fulham - with Emery hoping to rely on the return from injury of Aaron Wan-Bissaka.
Pau Torres and Victor Lindelof should continue as the centre back pairing, with Ian Maatsen the only option available at left back.
Joao Gomes, who had a torrid time of it in Villa's 3-0 UEFA Champions League defeat against Barcelona in midweek, should continue to partner Boubacar Kamara in the midfield pivot, while Johan Manzambi and John McGinn should keep their spots in attack.
Emiliano Buendia is likely to drop out of the starting XI, with Ibrahim Mbaye set to come in off the left, behind Nicolas Jackson, who has scored eight goals in 12 games so far this season.
Predicted Manchester United lineup
(4-2-3-1): Senne Lammens; Leny Yoro, Harry Maguire, Ayden Heaven, Diogo Dalot; Andrey Santos, Youri Tielemans; Matheus Cunha, Bruno Fernandes, Amad Diallo; Bryan Mbeumo.
Predicted Aston Villa lineup
(4-2-3-1): Zion Suzuki; Aaron Wan-Bissaka, Victor Lindelof, Pau Torres, Ian Maatsen; Joao Gomes, Boubacar Kamara; Ibrahim Mbaye, Johan Manzambi, John McGinn; Nicolas Jackson.
