All 30 MLB teams will be in action on Sunday to close out the week, which will include an Interleague matchup between the San Diego Padres and the Seattle Mariners, with an expected first pitch time of 7:20 PM ET.
The game will be played at T-Mobile Park in Seattle, Washington and will be broadcast on both Peacock and NBC.
Padres vs. Mariners betting picks and predictions
Seattle Mariners ML (-160)
Our top pick for this game is backing the Mariners to win. Seattle has been floating around .500 most of the season so far and enter this game with a record of 22-25. The Mariners lost both Game 1 and Game 2 of this series, but will be looking to avoid a sweep as they are scheduled to start George Kirby.
The right-hander is widely known as the Mariners’ ace or at the very least, one of their top pitching options. Kirby has the numbers to back it up as well, considering that he is 5-2 on the season and has an ERA of 2.84.
Not only have his overall numbers been excellent this season, but he has been just as good, if not better when pitching at home. Over five home starts this season, Kirby is 3-1 and has an ERA of 2.78, while he has allowed only 10 earned runs over 32.1 innings.
San Diego, on the other hand, enters this game with a record of 27-18, having won their second game in a row on Saturday night. The Padres are set to start Lucas Giolito, who will be making his 2026 debut.
Even though Giolito had solid numbers in 2025, it could take him at least a few starts to get up to speed. For that reason, backing the Mariners to win behind another strong outing from Kirby is the best option.
Luke Raley to Hit a Home Run (+475)
Look for Seattle's Luke Raley to hit a home run too. Raley has had a solid start to the season, hitting .264, while he leads the Mariners in home runs with 10.
On top of that, Raley has hit all 10 of his home runs against right-handed pitchers, which is what Giolito is. Additionally, five of Raley’s 10 home runs have been at home and he has homered in two of his last four games.
There is also the fact that Giolito will be making his first start of 2026 and therefore might not be at his top level, and Raley is in the sort of form to capitalize in the best possible way.
Read more betting picks and predictions for the MLB on site.
Padres vs. Mariners odds
Padres | +135 |
Mariners | -160 |
Run Line | SEA Mariners -1.5 |
Total | O/U 7.5 |
Padres vs. Mariners player props
Player home run odds
Julio Rodriguez (Mariners) | +400 |
Josh Naylor (Mariners) | +475 |
Luke Raley (Mariners) | +475 |
Fernando Tatis Jr. (Padres) | +600 |
Manny Machado (Padres) | +625 |
Jackson Merrill (Padres) | +650 |
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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
