The Buffalo Bills will put their perfect winning record away from home on the line again on Sunday, as they head to Allegiant Stadium to take on the Las Vegas Raiders on Sunday.
Narrowly overcoming both the Houston Texans and the Los Angeles Rams in their two road games so far this term, the Bills have shown they can grind it out on their travels.
The Raiders head into this contest on the back of two defeats against the Kansas City Chiefs and New England Patriots.
This tricky schedule continues for the Raiders into this Week 6 clash and they might well be up against it when they host the Bills in Nevada.
Las Vegas Raiders v Buffalo Bills Betting Tips
Best Bet – Bills -5.5 @ 25/27
Alternative Bet – James Cook III over 100 yards rushing @ 11/10
Bet Builder – Over 51.5 total points and James Cook, Josh Allen & Brock Bowers anytime touchdown scorers @ 5/1
Las Vegas Raiders v Buffalo Bills Prediction
Best Bet: Bills -5.5 @ 25/27
Winning 36-31 at the Texans and 37-34 at the Rams, there have been some nail-biting away wins already for the Bills this season.
Certainly banged up on offence with injuries in the wide receiver department, Buffalo have still managed to reach the summit of the AFC East with a 4-1 record going into Week 6.
The Bills are backed to improve that record to 5-1 in Nevada this weekend, against a Raiders side who have simply been leaking too many points on defence.
Going into this encounter on the back of a 30-27 home defeat to the Chiefs and a 45-17 thrashing at the Patriots, this fragile Las Vegas defence is there for the taking.
The Bills have won the last three meetings with the Raiders and Buffalo are fancied to not only win on Sunday at Allegiant Stadium, but cover the spread in the process.
Alternative Bet: James Cook III over 100 yards rushing @ 11/10
With Buffalo’s wide receiver lineup weakened due to injuries, the emphasis is likely to be on the ground game again this weekend.
James Cook III has had some fumbling issues but when the ball is locked into his arms he’s a dangerous operator, capable of amassing significant yardage.
Looking back at his five appearances this season in the NFL, Cook has passed the 100-yard rushing mark on three occasions, including in his last game with 111 yards against the Rams.
Given he’s run for over 100 yards in three of his last four games, Cook gets the nod at 11/10 to break that 100-yard rushing barrier again on Sunday.
Las Vegas Raiders v Buffalo Bills Bet Builder Tip
Over 51.5 total points
James Cook anytime touchdown
Josh Allen anytime touchdown
Brock Bowers anytime touchdown
Pays 5/1
Going for over 51.5 total points would have landed comfortably in both of the Bills’ away games so far this season and, given how the Raiders have been defending of late, this Bet Builder backs that trend to continue.
Meanwhile, James Cook, Josh Allen and Brock Bowers are all fancied to score touchdowns this weekend in Vegas.
Cook has scored touchdowns in all of his last four appearances, including a brace last time out against the Rams.
Of course dangerous through the air, quarterback Allen is also a threat on the ground and has already scored eight rushing touchdowns this season.
Allen is backed to go over for another this weekend, as is Raiders tight end Brock Bowers, who has scored in all of his last three appearances for Las Vegas.
Key Match Stats
The Buffalo Bills have won both of their two away games so far this season
The Bills are sitting pretty at the top of the AFC East with a 4-1 record
The Las Vegas Raiders are third in the AFC West with a 3-2 record
The Raiders go into this game following back-to-back defeats to the Kansas City Chiefs and the New England Patriots
The Bills have won all of their last three meetings with the Raiders
Tactics, Form and Team News
The Raiders will be without defensive tackle Tonka Hemingway for Sunday's clash with the Bills after he suffered a concussion in last week's defeat to the New England Patriots.
Wide receiver Jalen Nailor is set to return after missing the previous game due to a concussion
Rookie offensive lineman Trey Zuhn III remains questionable with a knee injury, while the hosts will also be without wide receiver Dont'e Thornton Jr. and tight end Carter Runyon.
As for the Bills, the visitors have five players listed as questionable, including wide receivers D.J. Moore and Joshua Palmer, who are both nursing shoulder injuries.
Ed Oliver is also a doubt with a knee problem, while fellow defensive tackle T.J. Sanders and cornerback Dee Alford are battling shoulder and ankle injuries respectively.
In more positive news for the Bills, right tackle Spencer Brown is expected to play after recovering from back spasms sustained in the overtime win against the Rams last time out.
Read more NFL betting tips and predictions on site.
This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
