Only a point separated Brentford and Sunderland in last season's Premier League, but home advantage may count again when they clash on Saturday.
The Bees have made a strong start to the season, beating Tottenham 3-0 and drawing 1-1 at Leeds, either side of a 6-1 EFL Cup triumph away at Birmingham.
Sunderland lost their league opener 2-1 at Ipswich, but responded to beat Fulham 1-0. However, they may struggle at the Gtech.
Brentford won 3-0 when this pair met in West London in January, avenging their 2-1 loss on Wearside the previous August, and Keith Andrews' settled side could prove too good for the Black Cats.
Best Bet - Brentford to win to nil @ 7/4
Alternative Bet - Igor Thiago first goalscorer @ 10/3
Bet Builder - Nathan Collins 2+ Shots, Enzo Le Fee 2+ Shots & Reinaldo Mandava 2+ Fouls Committed @ 10/1
Best Bet: Brentford to win to nil @ 7/4
Sunderland are preparing for their first European campaign since 1973/74 and Regis Le Bris looks to have added well ahead of their foray into the Europa League.
Kevin Danso and Malick Fofana could make their debuts on Saturday, but the worry is their bows could be in a losing cause.
The Black Cats have a shocking record in London, winning only two of their last 16 top-flight trips to the capital.
They have lost their last three, conceding three times on each occasion, including last season's defeat to Brentford.
The Bees blew Spurs away in their opener and were unlucky not to get more at Leeds, totalling 22 shots.
That result means that the home side are unbeaten in the Bees' last 12 home fixtures.
Sunderland's blank at the Gtech last season contributed to them averaging less than a goal a game on the road and Andrews' hosts can win again with a clean sheet.
Alternative Bet - Igor Thiago first goalscorer @ 10/3
Igor Thiago's 22 Premier League goals last season earned him a place in Brazil's World Cup squad and included three strikes against Sunderland.
After opening the scoring in the defeat at the Stadium of Light, he scored twice in the return match, again breaking the deadlock.
Thiago has yet to score this season, but the underlying numbers are good: seven shots, two on target.
Averaging 3.66 shots per 90 minutes, it feels only a matter of time before the 25-year-old breaks his duck for the campaign and he will fancy his chances against an opponent he thrived against last season.
Nathan Collins 2+ Shots
Enzo Le Fee 2+ Shots
Reinaldo Mandava 2+ Fouls Committed
Pays 10/1
Brentford skipper Nathan Collins has had five efforts on goal from his two appearances and is a great price to continue that trend and get this Bet Builder off to a strong start.
Sunderland may have blanked at the Gtech last season but Enzo Le Fee registered two shots at goal, consistent with his four attempts already in 2026/27.
The Frenchman and his team-mates may be frustrated again, and that could spill over into indiscipline.
Black Cats' defender Reinaldo Mandava has already conceded five fouls this season. The Mozambican rarely shirks a tackle and could enjoy a real duel with Brentford's attacking right-back, Michael Kayode.
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The home side is unbeaten in Brentford's last 12 games.
Sunderland have won only two of their last 16 top-flight away games in London (D2, L12).
Both sides won the home fixture in this head-to-head last season.
Igor Thiago scored 22 Premier League goals in 2025/26, three of them against Sunderland.
Brentford's Nathan Collins is averaging 2.5 efforts at goal a game in 2026/27.
Sunderland's Enzo Le Fee has registered four shots this season.
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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.