India lost all six completed T20Is on their tour of Ireland and England in July but they outclassed Afghanistan in Sunday's series opener in Delhi.
The T20 World Cup holders are almost at full strength, welcoming back key bowlers Jasprit Bumrah and Varun Chakravarthy, leaving Afghanistan as 10/1 outsiders for Tuesday's game at the Arun Jaitley Stadium.
Best Bet - India highest individual score - Over 61.5 @ 5/6
Alternative Bet - Sediqullah Atal top Afghanistan batter @ 10/3
Bet Builder - Abhishek Sharma 2+ sixes, Arshdeep Singh 2+ wickets & Azmatullah Omarzai most sixes for Afghanistan @ 11/1
Best Bet: India highest individual score - Over 61.5 @ 5/6
India reduced Afghanistan to 43-5 after seven overs of the first T20I before Azmatullah Omarzai (64 not out) and Mohammad Nabi (33) dragged them to 156-8.
That target never looked likely to trouble India, whose opener Abhishek Sharma cracked 82 off just 32 balls in the chase.
Abhishek was supported by number three Ishan Kishan (42), whose previous two T20I scores in Delhi were 76 against South Africa and 61 against Namibia.
Opener Sanju Samson was dismissed for 10 on Sunday, but he had finished this year's triumphant T20 World Cup campaign with knocks of 97 not out, 89 and 89.
At least one of India's top three should go big on Tuesday, particularly if the hosts bat first, so it is worth backing any home batter to score over 61.5.
Delhi's Arun Jaitley Stadium produced some high-scoring matches in this year's IPL.
India's T20 captain Shreyas Iyer's unbeaten 71 powered Punjab Kings to a target of 265 in a game in April that also featured individual scores of 152 not out, 91 and 76.
Alternative Bet: Sediqullah Atal top Afghanistan batter @ 10/3
Afghanistan number three Sediqullah Atal made only 13 on Sunday but his innings included two eye-catching boundaries - one four and one six - off India's pace ace Jasprit Bumrah.
Atal looks a good bet to top-score on Tuesday, having impressed with knocks of 45, 27, 143 and 98 during August's ODI series in Ireland.
He has also put together a decent run of T20I scores. In September 2025, he made 54 against the UAE, 64 against Pakistan and an unbeaten 73 against Hong Kong.
Another half-century followed against the West Indies in January and Atal signed off his T20 World Cup campaign with 44 off 32 balls against Canada in Chennai.
Abhishek Sharma 2+ sixes
Arshdeep Singh 2+ wickets
Azmatullah Omarzai to hit most sixes for Afghanistan
Pays 11/1
India opener Abhishek hit seven sixes in the first T20I and has cleared the ropes 21 times in eight T20 innings at Delhi's Arun Jaitley Stadium.
Arshdeep Singh was right on the money in the series opener, claiming 3-19 and the left-arm quick has taken nine wickets in his last three T20Is against Afghanistan.
Afghan all-rounder Azmatullah Omarzai saved his side from a far heavier defeat on Sunday, hitting four sixes in his unbeaten 64, and he struck five maximums from just 27 balls for Punjab Kings in this season's IPL.
Learn more about how Bet Builders work in our Bet Builder guide.
Afghanistan have lost all nine of their previous T20Is against India
The Afghans had an opening stand of 35 or more in four of their last six T20Is
Leg-spinner Rashid Khan has taken only three wickets in four T20Is against India
India have won 12 of their 14 home T20Is in 2026
Ishan Kishan has scored 76, 61 and 42 in three T20I appearances in Delhi
Abhishek Sharma has hit 60 sixes in 25 T20I innings in India
Afghanistan fast bowler Naveen-ul-Haq was not fully fit for the first game of the series, but he is pushing for a first international outing since December 2024.
Predicted Afghanistan XI: 1 Rahmanullah Gurbaz (wk), 2 Ibrahim Zadran (c), 3 Sediqullah Atal, 4 Gulbadin Naib, 5 Darwish Rasooli, 6 Azmatullah Omarzai, 7 Mohammad Nabi, 8 Rashid Khan, 9 Noor Ahmad, 10 Mujeeb Ur Rahman, 11 Fazalhaq Farooqi.
India opted for experienced openers Abhishek and Samson instead of youngster Vaibhav Sooryavanshi in Sunday's first T20I.
Fast bowler Bumrah will be assessed after making his first appearance for two months, but paceman Harshit Rana and all-rounder Hardik Pandya are injured.
Predicted India XI: 1 Sanju Samson (wk), 2 Abhishek Sharma, 3 Ishan Kishan, 4 Shreyas Iyer (c), 5 Tilak Varma, 6 Nitish Kumar Reddy, 7 Shivam Dube, 8 Axar Patel, 9 Varun Chakravarthy, 10 Jasprit Bumrah, 11 Arshdeep Singh.
Read more cricket betting tips and predictions on site.
This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.