Arsenal entertain LOSC Lille looking to extend their 100% record in the UEFA Champions League on Tuesday night.
The Gunners reached the final of Europe's elite club competition last season, only to suffer an agonising defeat as Gabriel Magalhaes' skied penalty handed Paris Saint-Germain their second UEFA Champions League crown.
Arsenal chalked up a 1-0 victory over Napoli at the Stadio Diego Armando Maradona through Martin Odegaard's second half strike and they will be looking to follow that up when Davide Ancelotti's Lille rock up to north London.
The Ligue 1 outfit suffered defeat in their opening league phase fixture as they were beaten by Real Betis in a 3-2 thriller despite taking the lead twice, but Les Dogues are going strong in France's top-flight and sit second with four wins from their opening six matches.
Mikel Arteta has been handed a selection headache on the eve of Tuesday's fixture with Martin Zubimendi and Piero Hincapie added to the treatment table.
The pair sustained ankle injuries in a post-match training session following the victory over Leeds United on Saturday and have been ruled out of the clash against Lille.
Hincapie would likely have started over Ricciardo Calafiori with the Italian enduring a busy schedule in recent weeks. Myles Lewis-Skelly might now be preferred at left-back.
Arteta will be keen to manage his squad during a relentless period and that will lead to rotation across numerous positions. Jurrien Timber is expected to take Ben White's place at right-back, while Cristhian Mosquera will be vying for a starting berth alongside Gabriel Magalhaes.
Zubimendi's absence means Declan Rice and Bruno Guimaraes are primed to start in midfield, but Martin Odegaard might be rested which could provide Mikel Merino with an opportunity to stake a claim for increased minutes.
Viktor Gyokeres and Eberechi Eze are likely to come in for Kai Havertz and Noni Madueke as Bukayo Saka continues on the right.
As for the visitors, Ethan Mbappe is suspended for this fixture, but he would have missed the trip to London anyway after picking up an injury whilst representing France's Under-21s.
Hamza Igamane is a long-term absentee, while right-back Tiago Santos is set for a prolonged period on the sidelines after suffering a severe knee injury during the win over Le Havre.
Former Arsenal striker Oliver Giroud makes an emotional return to the Emirates. The Frenchman made his first start since early September during Saturday's victory and will be hoping to lead the line ahead of Ayase Ueda.
Predicted Arsenal team
David Raya
Jurrien Timber
Cristhian Mosquera
Gabriel Magalhaes
Myles Lewis-Skelly
Declan Rice
Bruno Guimaraes
Bukayo Saka
Mikel Merino
Eberechi Eze
Viktor Gyokeres
Predicted LOSC Lille team
Berke Ozer
Nathan Ngoy
Tanguy Nianzou
Alexsandro
Romain Perraud
Benjamin Andre
Nabil Bentaleb
Dilane Bakwa
Hakon Arnar Haraldsson
Gaetan Perrin
Olivier Giroud
