Villarreal CF host SSC Napoli on matchday two of this season's UEFA Champions League and both clubs are aiming to bounce back from opening defeats.
Villarreal were beaten 3-2 by Borussia Dortmund in a thrilling game in Germany while Napoli lost 1-0 at home to last season's runners-up Arsenal FC.
Villarreal CF v SSC Napoli Tips Summary
Best Bet - Draw @ 27/10
Alternative Bet - Kevin De Bruyne to score or assist @ 11/10
Bet Builder - Under 3.5 goals, Nathan Saliba 2+ shots & Santiago Mourino to be booked @ 6/1
Villarreal CF v SSC Napoli Prediction
Best Bet: Draw @ 27/10
Villarreal and Napoli have both made patchy starts to the 2026/27 season and the draw looks the best bet when they meet at the Estadio de la Cerámica.
Napoli were comprehensive 3-0 winners at home to Frosinone in Serie A on Saturday but they have lost their three toughest fixtures this term.
They have faced two of their fellow UEFA Champions League contenders in Serie A, losing 2-1 to Como 1907 and 3-2 to FC Internazionale Milano.
And they struggled to land a blow on Premier League champions Arsenal in a 1-0 home defeat on matchday one.
The Gunners outshot Napoli 26-5 but had to wait until the 75th minute for captain Martin Odegaard to break the deadlock.
Another tight contest looks likely when Napoli travel to Villarreal, who have won only two of their nine matches in all competitions this season.
They beat Malaga and Levante, both by a 3-1 margin, in La Liga before the international break but were brought down to earth at the weekend by Real Madrid C.F.
Real Madrid won 1-0 in an ill-tempered game at the Estadio Santiago Bernabéu and Villarreal had a dismal record in last season's UEFA Champions League.
They finished 35th out of 36 teams in the league phase, picking up just one point from eight games, and their struggles continued with a 3-2 defeat at Borussia Dortmund on matchday one.
Alternative Bet: Kevin De Bruyne to score or assist @ 11/10
Napoli's 35-year-old playmaker Kevin De Bruyne remains a top-class creative force and he has enjoyed a productive month for club and country.
De Bruyne scored six goals in six appearances for Belgium during 2026 World Cup qualifying and also impressed at the start of their 2026/27 Nations League campaign.
The former Manchester City star set up Mika Godts's opener against Italy and scored twice in Belgium's 3-0 home victory over Turkey.
De Bruyne had 10 shots in three Nations League starts against Italy, France and Turkey before inspiring Napoli to a weekend win over Frosinone.
He scored his second and third goals of the Serie A season and Napoli's main penalty taker looks a tasty bet to contribute a goal or an assist against Villarreal.
Villarreal CF v SSC Napoli Bet Builder Tip
Under 3.5 goals
Nathan Saliba 2+ shots
Santiago Mourino to be booked
Pays 6/1
Under 3.5 goals was a winning bet in six of Napoli's first seven matches this season and Villarreal lost 1-0 at Real Madrid at the weekend.
Canada international Nathan Saliba should start in the number-10 role for Villarreal. He scored against Qatar at the World Cup and had three shots in his last La Liga appearance against Levante.
Villarreal right-back Santiago Mourino looks a good bet to be booked on Tuesday. He was cautioned against Borussia Dortmund on matchday one of the UEFA Champions League and has picked up two yellow cards in four league starts this term.
Learn more about how Bet Builders work in our Bet Builder guide.
Key Match Stats
Both of Villarreal CF's wins this season were by a 3-1 margin
Alberto Moleiro has contributed two goals and two assists in his last three La Liga games
Villarreal have won only two of their nine league and cup games in 2026/27
SSC Napoli conceded just two first-half goals in seven matches
Kevin De Bruyne has scored four goals in his last two appearances for Belgium and Napoli
Napoli have lost three of their last six games in all competitions
Read more football betting tips and predictions on site.
This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
