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Carolina Panthers vs. Philadelphia Eagles Picks & Predictions Graphic
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Panthers vs. Eagles Predictions, Player Props & Best Bets

Carolina Panthers will look to pick up where they left off when they face Philadelphia Eagles at Lincoln Financial Field in Week 6 of the 2026 NFL season on Sunday.

Carolina beat Detroit Lions 32-26 in Week 4, before their bye last week and, despite having a week to rest up, they are still top of the NFC South.

Philadelphia are 2-3 for the season and second in the NFC East, but they have a number of injuries to deal with and will be up against it, even on home turf this weekend.

Panthers vs. Eagles betting picks & predictions

Carolina Panthers -3.5 (-109)

Carolina was originally listed as the outsider for this clash, but an injury to Eagles quarterback Jalen Hurts means the market has flipped in favor of the Panthers.

Hurts has a blood clot in his calf and his return date is unknown, meaning Tanner McKee is set to start for just the third time.

Philadelphia already has running back Saquon Barkley and wide receiver DeVonta Smith listed as questionable, while fellow pass catchers Dontayvion Wicks and Hollywood Brow have also been added to the questionable list.

Center Drew Kendall and guard Tyler Steen have also got to prove their fitness and the Eagles come into this game on a short week after a return from London.

Carolina are fit and raring to go after their break and they should be able to hand Philadelphia a fourth successive defeat.

Bryce Young over 250 passing yards (+105)

Carolina have made a positive start to the season thanks to the form of quarterback Bryce Young.

Young has completed 62.3 per cent of his passes and he has already reached 1,268 yards after just four games.

The 25-year-old has surpassed 285 passing yards in every game and he has every chance of repeating that feat.

With Philadelphia's offense decimated by injuries, they may struggle to stay on the field and it could be a long afternoon at the office for the Eagles' defense.

Philadelphia have already allowed 238.8 passing yards per game and that total is bound to increase due to their ongoing injury woes.

After a week to rest and prepare, Young should be able to produce another solid display on the road.

Chuba Hubbard over 100 rushing and receiving yards (+115)

Carolina looks set for a big day on offense and running back Chuba Hubbard will be crucial to their chances of picking up another victory.

The Panthers may not get a better opportunity to beat the Eagles on the road than this for some time and Hubbard will look to build on his last two appearances.

He has rushed for 80 yards or more in two consecutive games and has 84 receiving yards to his name this season.

Hubbard is capable of causing problems as a pass catcher and while the Panthers have not used him that much in that department, he could rush for 100 yards alone this week.

Carolina will be happy to run down the clock if they have plenty of possession, so expect Hubbard to see plenty of the ball at Lincoln Financial Field.

Read more betting picks and predictions for the NFL on site.

Panthers vs. Eagles odds

Carolina Panthers

-169

Philadelphia Eagles

+144

Spread

CAR Panthers -3.5

Total

O/U 38.5

Panthers vs. Eagles player props

Anytime touchdown

Chuba Hubbard (CAR Panthers)

-135

Saquon Barkley (PHI Eagles)

+110

Dameon Pierce (PHI Eagles)

+175

Tetairoa McMillan (CAR Panthers)

+170

DeVonta Smith (PHI Eagles)

+195

Dontayvion Wicks (PHI Eagles)

+270

Read the latest NFL news on site.

This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.

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