Week 1 perfectly summed up college football in 2026: hectic and controversial.
UMass won their first game since 2024 against a Big Ten opponent - Rutgers, Boise State battled with Oregon throughout the game, Lane Kiffin and LSU dismantled Dabo Swinney and Clemson, while the "Bail Mary" in Ann Arbor took over all the headlines Saturday night.
The action continued on the following Sunday and Monday - where Ole Miss and SMU hit game-winning field goals against their respective opponents in Louisville and Florida State.
No. 1 Ohio State at No. 4 Texas headlines what should be another exciting slate of games in the early portion of the 2026 season. Below are the main line odds for all of the ranked matchups in Week 2, with odds provided by bet365:
Thursday, Sep. 10
Florida A&M @ No. 7 Miami (FL)
Spread | Total (O/U) | Money | |
Florida A&M | +59.5 -110 | O 65.5 -110 | - |
Miami (FL) | -59.5 -110 | U 65.5 -110 | - |
Friday, Sep. 11
Norfolk State @ No. 25 Virginia
Spread | Total (O/U) | Money | |
Norfolk State | +44.5 -105 | O 54.5 -120 | - |
Miami (FL) | -44.5 -115 | U 54.5 +100 | - |
Villanova @ No. 24 Louisville
Spread | Total (O/U) | Money | |
Villanova | +36.5 -110 | O 56.5 -110 | +3000 |
Louisville | -36.5 -110 | U 56.5 -110 | -25000 |
No. 23 Missouri @ Kansas
Spread | Total (O/U) | Money | |
Missouri | -5.5 -110 | O 51.5 -110 | -210 |
Kansas | +5.5 -110 | U 51.5 -110 | +175 |
Saturday, Sep. 12
Arizona State @ No. 10 Texas A&M
Spread | Total (O/U) | Money | |
Arizona State | +14.5 -115 | O 50.5 -110 | +500 |
Texas A&M | -14.5 -105 | U 50.5 -110 | -700 |
Howard @ No. 5 Indiana
Spread | Total (O/U) | Money | |
Howard | +56.5 -110 | O 65.5 -110 | - |
Indiana | -56.5 -110 | U 65.5 -110 | - |
No. 11 Oklahoma @ Michigan
Spread | Total (O/U) | Money | |
Oklahoma | -5.5 -110 | O 43.5 -110 | -225 |
Michigan | +5.5 -110 | U 43.5 -110 | +185 |
Read our partner authors' expert betting picks and predictions article for Oklahoma vs. Michigan on site.
No. 6 Oregon @ Oklahoma State
Spread | Total (O/U) | Money | |
Oregon | -23.5 -110 | O 57.5 -110 | -2400 |
Oklahoma State | +23.5 -110 | U 57.5 -110 | +1200 |
Read our partner authors' expert betting picks and predictions article for Oregon vs. Oklahoma State on site.
No. 16 Penn State @ Temple
Spread | Total (O/U) | Money | |
Penn State | -23.5 -115 | O 49.5 -110 | -3500 |
Temple | +23.5 -105 | U 49.5 -110 | +1500 |
No. 12 Alabama @ Kentucky
Spread | Total (O/U) | Money | |
Alabama | -10.5 -110 | O 49.5 -110 | -425 |
Kentucky | +10.5 -110 | U 49.5 -110 | +325 |
Arizona @ No. 15 BYU
Spread | Total (O/U) | Money | |
Arizona | +7.5 -110 | O 47.5 -110 | +240 |
BYU | -7.5 -110 | U 47.5 -110 | -300 |
Rice @ No. 3 Notre Dame
Spread | Total (O/U) | Money | |
Rice | +44.5 -110 | O 55.5 -110 | - |
Notre Dame | -44.5 -110 | U 55.5 -110 | - |
Utah State @ No. 19 Washington
Spread | Total (O/U) | Money | |
Utah State | +26.5 -110 | O 55.5 -110 | +1600 |
Washington | -26.5 -110 | U 55.5 -110 | -5000 |
UC Davis @ No. 17 SMU
Spread | Total (O/U) | Money | |
UC Davis | +26.5 -105 | O 58.5 -110 | +1250 |
SMU | -26.5 -115 | U 58.5 -110 | -2500 |
Southern @ No. 22 Houston
Spread | Total (O/U) | Money | |
Southern | +51.5 -110 | O 60.5 -115 | - |
Houston | -51.5 -110 | U 60.5 -105 | - |
No. 18 Tennessee @ Georgia Tech
Spread | Total (O/U) | Money | |
Tennessee | -12.5 -110 | O 55.5 -105 | -500 |
Georgia Tech | +12.5 -110 | U 55.5 -115 | +375 |
Iowa State @ No. 21 Iowa
Spread | Total (O/U) | Money | |
Iowa State | +13.5 +100 | O 40.5 -110 | +450 |
Iowa | -13.5 -120 | U 40.5 -110 | -600 |
Louisiana Tech @ No. 8 LSU
Spread | Total (O/U) | Money | |
Louisiana Tech | +35.5 -115 | O 55.5 -110 | +3300 |
LSU | -35.5 -105 | U 55.5 -110 | -40000 |
No. 1 Ohio State @ No. 4 Texas
Spread | Total (O/U) | Money | |
Ohio State | +1.5 -110 | O 49.5 -110 | +100 |
Texas | -1.5 -110 | U 49.5 -110 | -120 |
No. 13 Texas Tech @ Oregon State
Spread | Total (O/U) | Money | |
Texas Tech | -26.5 -110 | O 53.5 -115 | -5000 |
Iowa | +26.5 -110 | U 53.5 -105 | +1600 |
Charlotte @ No. 9 Ole Miss
Spread | Total (O/U) | Money | |
Charlotte | +47.5 -110 | O 60.5 -115 | - |
Ole Miss | -47.5 -110 | U 60.5 -105 | - |
Arkansas @ No. 20 Utah
Spread | Total (O/U) | Money | |
Arkansas | +12.5 -105 | O 54.5 -115 | +375 |
Utah | -12.5 -115 | U 54.5 -105 | -500 |
UL Lafayette @ No. 14 USC
Spread | Total (O/U) | Money | |
UL Lafayette | +30.5 -105 | O 59.5 -110 | +2500 |
USC | -30.5 -115 | U 59.5 -110 | -10000 |
All odds written in this article were correct at the time of writing and are subject to change.
