With no Rugby Championship this year, Australia and South Africa meet in a one-off Test in Perth on Sunday.
The Springboks have been busy, completing a 3-1 victory in their Rugby's Greatest Rivalry series against New Zealand on 12th September.
They have demonstrated their depth by making 13 changes from that 43-28 win a fortnight ago in Baltimore, with only lock Eben Etzebeth and wing Ethan Hooker retained.
Australia have also kept themselves ticking over with series wins over Japan and Argentina.
After losing their first two Nations Championship matches in July, they are now unbeaten in five, most recently drawing 28-28 with the Pumas.
They have named Joseph-Aukuso Suaalii on the wing. Usually a centre, or occasionally a full-back, he will run on as a winger for the first time at either club or international level.
His selection nods to countering the Boks' aerial game, but it may also be a chance to see whether more space brings out the best in the rugby league convert.
With this being both countries' final game before a break and then November's northern hemisphere phase of the Nations Championship, expect plenty of physicality, but most likely an away victory.
Best Bet - Double Result - Australia - South Africa @ 5/1
Alternative Bet - Max Jorgensen anytime tryscorer @ 11/8
Bet Builder - Over 53.5 points, Edwill van der Merwe anytime tryscorer & Malcolm Marx anytime tryscorer @ 17/4
Best Bet: Double Result - Australia - South Africa @ 5/1
Rassie Erasmus may have made 13 changes, but while that helps build squad depth, keep players fresh and simultaneously gives others minutes, he has selected certain individuals for specific roles.
For instance, he says Marco van Staden may scrummage at number eight but his main role is to battle for the ball on the ground like the openside he usually is.
It will inevitably take a while for the Boks to gel and that will be a leveller. However, they have experience across the park.
They also have amazing talent on the bench, with forward replacements Malcolm Marx, Ox Nche, Wilco Louw, Lood de Jager and Jasper Wiese likely starters if the World Cup final were tomorrow.
Although South Africa were level or ahead at the break in each of their last 12 games the Wallabies' more familiar partnerships may help them build a lead.
They have won the race to 10 points in seven of their last eight matches, but like in their Nations Championship defeats to France and Ireland, the hosts could be pegged back and suffer another frustrating loss.
Alternative Bet: Max Jorgensen anytime tryscorer @ 11/8
The Wallabies still have a massive attacking threat, though, and, while Suaalii's selection on the left wing has gained headlines, the player on the opposite side, Max Jorgensen, is arguably more dangerous.
A rangy, elusive runner, Jorgensen scored tries against Japan and Argentina.
The 22-year-old also dotted down on both occasions these teams met in 2025, making him a live chance for another score.
Over 53.5 Points
Edwill van der Merwe anytime tryscorer
Malcolm Marx anytime tryscorer
Pays 17/4
With this being both teams' final match before a month off and their northern hemisphere fixtures, it could have an end-of-term feel.
Australia tend to be involved in high-scoring affairs, with only one of their last nine outings not featuring 56 or more points, so backing over 53.5 points gives this bet builder some wriggle room.
With all the talk about Australia's wingers, South Africa's flyers have been overlooked and their number 14, Edwill van der Merwe, may go over.
He has scored in his last four appearances for either the Sharks or his country and notched six tries in his seven international caps.
Finally, look for Marx to go over off the bench. He has scored five career tries against Australia and this might be his last game for a while.
The hooker's importance makes him a candidate to be wrapped in cotton wool, with an eye on next year's Rugby World Cup, and he has been named on the bench in the past but introduced in the first half.
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South Africa have won five of the last six meetings
The Springboks have lost only one of their last 17 fixtures
Australia are unbeaten in five matches
They have won the race to 10 points in seven of their last eight matches
Wallaby winger Max Jorgensen scored tries in both of last year's meetings with the Springboks
South Africa hooker Malcolm Marx has scored five career tries against Australia
Team-mate Edwill van der Merwe scored on his last international appearance in Argentina
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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.