Manchester United play host to Roma looking for their first win in nearly two months.
The Red Devils haven't won any of their last nine matches in all competitions, and while no fixture looks appealing at the moment, a tie with free-scoring Roma doesn't seem particularly welcome.
Roma have scored 16 goals in their last four games and found themselves 3-1 up to Real Madrid earlier in the season before shipping three late goals to lose 4-3.
United boss Michael Carrick continues to contest with a number of injury issues as he desperately tries to save his job prior to the international break.
Lisandro Martinez is available for selection after being sent off against Chelsea on Saturday, with the Argentine set to serve his suspension against Aston Villa at the weekend, but Michael Carrick has dropped the defender to the bench with Ayden Heaven taking his place.
Patrick Dorgu and Kobbie Mainoo have been back in training after their lay-offs, though tonight's game comes soon for the former. Luke Shaw and Benjamin Sesko are ruled out, with Marcus Rashford also unavailable. Mainoo returns to the starting XI alongside Carlos Baleba.
The visitors are without Muhammed Bah, Paulo Dybala, Manu Kone, Lorenzo Pellegrini and Mile Svilar through injury, while Pierluigi Gollini, once on the books at Manchester United, also misses out with a back complaint.
Senne Lammens
Leny Yoro
Harry Maguire
Ayden Heaven
Diogo Dalot
Carlos Baleba
Kobbie Mainoo
Amad Diallo
Bruno Fernandes
Matheus Cunha
Bryan Mbeumo
Substitutes: Darlow, Heaton, Amass, De Ligt, Martinez, Mazraoui, Santos, Mount, T Fletcher, Tielemans, Lacey, Zirkzee
Vasquez
Balerdi
Gianluca Mancini
Mario Hermoso
Devyne Rensch
Marten de Roon
Rodrigo Mora
Wesley
Bryan Cristante
Matias Soule
Donyell Malen
Substitutes: Koulierakis, Ndicka, Castro, Molina, Pisilli, Di Nunzio, De Marzi, Lulli, Ghilardi
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