Inter Milan are without a point after two rounds of games in the UEFA Champions League and can ill afford a slip-up when Shakhtar Donetsk visit the San Siro.
The Nerazzurri played well in defeat away at Real Madrid in their opening game before losing a seven-goal thriller at home to Club Brugge on matchday two.
Shakhtar took a point in Eindhoven against PSV and then saw off AEK Athens at their home-from-home for this season, Stamford Bridge, but the Ukrainians have never beaten Inter in seven previous attempts.
Inter v FC Shakhtar Donetsk Prediction Tips Summary
Best Bet - Inter Milan to win & Both teams to score @ 6/5
Alternative Bet - Federico Dimarco to assist @ 7/4
Bet Builder - Over 3 goals, Marcus Thuram to score anytime, Gleiker Mendoza 1+ shots on target & Josep Martinez 3+ saves @ 12/1
Inter v FC Shakhtar Donetsk Prediction
Best Bet: Inter Milan to Win & Both teams to score @ 6/5
Inter Milan desperately need three points from this contest, but they might not have it their way against Shakhtar.
The Ukrainians have four points from games against PSV and AEK Athens, while Cristian Chivu's hosts have managed just two clean sheets in nine domestic and European outings.
At the San Siro, Inter have won with both teams scoring in three of five home matches this season.
However, they have not lost in seven previous contests against Shakhtar and will be all out to avoid a record fifth successive UEFA Champions League defeat.
Shakhtar have lost six of their last 10 games against Italian opposition and while they can get on the scoresheet, another defeat is forecast.
Alternative Bet: Federico Dimarco to assist @ 7/4
Federico Dimarco played in his trademark left wing-back role for Inter in the loss to Brugge, creating six chances, one of which Lautaro Martinez converted for Inter's first-half equaliser.
In the UEFA Champions League, Dimarco has now laid on seven assists for his teammates at Inter and had a superb tally of 18 assists in Serie A last season – twice as many as his nearest pursuers.
Inter will attack this contest and the experienced Italian international can grab another assist.
Inter v FC Shakhtar Donetsk Prediction Bet Builder Tip
Over 3 goals
Marcus Thuram to score anytime
Gleiker Mendoza 1+ shots on target
Josep Martinez 3+ saves
Pays 12/1
Goals should come at regular intervals. There has been a first-half goal in each of Shakhtar's last nine UEFA Champions League outings and the visitors have scored multiple times in each of their last five games.
Since the 2-1 defeat at Real Madrid, Inter's five games have produced 26 goals, averaging 5.20 per-game.
With talisman Lautaro Martinez on the injured list, Marcus Thuram can carry the burden. He has three goals in his last six starts.
Shakhtar should threaten and Gleiker Mendoza has scored in both UEFA Champions League games, and can land a shot on target.
There were 48 shots at goal in Inter's defeat to Club Brugge and Josep Martinez had to make four saves, alongside conceding four times.
He also made six stops against Real Madrid and can be included in this treble for at least three more.
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Key Match Stats
Inter have lost six of their last seven games in the UEFA Champions League, including both this season to Real Madrid and Club Brugge
Shakhtar Donetsk have four points from two matches, drawing away to PSV before beating AEK Athens at Stamford Bridge
These sides have met seven times previously, with Inter Milan winning three. Shakhtar have scored just one goal in those seven meetings
The Ukrainians are winless in 10 European fixtures against Italian opposition (D4 L6), scoring just once in that sequence
Shakhtar have won their last six games in all competitions and are unbeaten in eight
Inter have won six from seven in Serie A, drawing once.
Inter's last seven competitive games have featured three or more goals, with just one clean sheet in nine this season
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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.
