For the first time since 2006, there will be an American in the men's final of the US Open with compatriots Taylor Fritz and Frances Tiafoe locking horns in the semi-finals at Flushing Meadows.
This is uncharted territory for 12th seed Fritz, who has never before made the last four of a Grand Slam, while Tiafoe reached the 2022 US Open semi-finals.
Both players have excelled in front of a partisan New York this year, with Fritz booking his spot in the last four with a 7-6 3-6 6-4 7-6 triumph over fourth seed Alexander Zverev.
Tiafoe, meanwhile, was handed a walkover win against Grigor Dimitrov, having led 6-3 7-6 6-3 4-1 when his opponent retired injured.
Fritz has lost just once to Tiafoe in his career and he will be determined to outshine his compatriot again.
Tiafoe may have reached the final four at Flushing Meadows previously but Fritz also has experience of going deep in Grand Slams, twice reaching the quarter-finals at Wimbledon and also progressing to that stage of the Australian Open this year.
It’s been a promising season for Fritz and he would love nothing more than to cap it off by making the US Open final.
Fritz can draw plenty of confidence from the head-to-head record heading into this contest, with the 12th seed winning each of his last six meetings with Tiafoe, including a 6-3 6-4 triumph on the hard courts in Acapulco in their most recent encounter last year.
Both players have excelled in New York but Fritz has taken his game to the next level in the last week or so, showcasing a ruthless serve and dominance on the return.
He made light work of eighth seed Casper Ruud and fourth seed Zverev in the last two rounds and he should have the edge in this clash.
But it will be far from straightforward given Tiafoe's form, so to squeeze more value out of Fritz's price, bettors should back him to win and both players to win a set.
Whichever way bettors feel this match will go, it is highly likely it will be a blockbuster.
History beckons for both players as they bid to become the first American man since Andy Roddick in 2003 to win a major singles title.
There will be no shortage of incentive for either player and the way both have been serving suggests it could be a back-and-forwards kind of match.
Fritz's quarter-final with Zverev went to four sets but featured 45 games and Tiafoe's last-eight clash with Dimitrov involved 36 games despite the fourth set having not even been completed.
With that in mind, a bet on over 40.5 games could be another smart betting strategy for this semi-final.
These players look hard to split and there are reasons to back both of them, so if punters are wary of settling on one player to win, another way to play it could be by looking at the first set.
Bettors should not expect anything risky from either player in the opening set and it could be settled by just one break of serve or even a tiebreak.
Tiafoe has won all but one of his opening sets at this year's US Open and the same applies to Fritz, who edged the first set 7-6 against quarter-final opponent Zverev.
Neither player will want to give much away to begin with and a bet on over 10.5 games in the opening set of the contest appeals.
Taylor Fritz -250
Frances Tiafoe +200
This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.