Inter Miami vs. Vancouver Whitecaps: Picks, Predictions, Odds and Player Props

Lionel Messi's Inter Miami have it all to do to make the CONCACAF Champions League final heading into the second leg of their semifinal against Vancouver Whitecaps.

A 2-0 defeat by Vancouver last week at BC Stadium has given the Canadian side a massive advantage as they head to Florida.

But eight-time Ballon d'Or winner Messi knows a thing or two about pulling off miracles and he will relish the chance of adding another famous storyline to an incredible career.

Inter Miami vs. Vancouver Whitecaps betting picks and predictions

Inter Milan to qualify (+250)

Inter Miami overturned a one-goal deficit against LA Galaxy to move into the semifinals of the 2025 CONCACAF Champions Cup.

Now they need to overturn a two-goal deficit against Vancouver Whitecaps to reach the final and it could be well worthwhile backing them to pull it off.

Messi and co are +250 shots to qualify for June's final against the winners of the other semi, the all-Mexican duel between Tigres and Cruz Azul.

And if they carve out the chances at Chase Stadium that they failed to in British Columbia last week, then they are well capable of taming the Caps.

In last week's 2-0 loss in Vancouver, Inter had almost 70 percent possession and bossed the corner count 9-3. They dominated the ball - yet only mustered nine attempts and only two of those were on target.

Messi had a quartet of shots which failed to seriously trouble Vancouver keeper Yohei Takaoke and Tadeo Allende also wasted a couple of openings.

And Inter paid the price for that unusual absence of sharpness around the box with Brian White opening the scoring and then Sebastian Berhalter adding that critical second five minutes from time.

Inter lost again at the weekend - 4-3 at home to Dallas having blown a 3-1 lead but Javier Mascherano rested Messi, Sergio Busquets, Jordi Alba, Luis Suarez and others with all eyes focused on the rematch with Vancouver.

The Whitecaps have started their MLS campaign nicely enough, sitting atop their conference after 10 rounds.

Jesper Sorensen sent out a strong side as Pedro Vite scored twice in a 3-1 win at Minnesota at the weekend.

Inter have won all three home games in the CONCACAF Champions League, including 3-1 against LA Galaxy last time.

Vancouver have failed to win any of their three away ties, with a pair of 2-2 draws at Monterrey and Pumas UNAM having lost their opening-round trip to Deportivo Saprissa of Costa Rica, 2-1.

Tadeo Allende anytime scorer (+200)

Inter's Argentine winger Allende was as guilty as anyone for the Fort Lauderdale-based club not getting on the scoresheet in Vancouver.

Allende fluffed a couple of decent openings but at least posed something of a threat in a game where Inter were some way from their sharpest.

The 26-year-old Celta Vigo loanee signed off 2024 with a couple of goals for his parent club in the Copa del Rey before turning up in the Sunshine State in January.

A couple of goals in winter friendlies showed he would slot in nicely under compatriot Mascherano and alongside another Argentine legend in Messi, and he has generally produced well.

He scored in four successive matches - two in this competition - and is averaging 1.5 shots per game.

Vancouver's defense, although solid at home, has shipped two goals in each of the three away legs in this competition and that should offer real hope that Allende can get on the scoresheet.

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Inter Miami vs. Vancouver Whitecaps odds

Inter Miami	-188
Tie	+333
Vancouver Whitecaps	+475

Inter Miami vs. Vancouver Whitecaps player props

Anytime Goalscorer

Brian White (VW)	+260
Daniel Rios (VW)	+300
Ryan Gauld (VW)	+300
Lionel Messi (Inter)	-125
Luis Suarez (Inter)	-105
Tadeo Allende (Inter)	+200

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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.