Inter Miami vs. Philadelphia Union: Picks, Predictions, Odds and Player Props

Eastern Conference leaders Philadelphia Union head to Chase Stadium on Saturday night to take on a formidable Inter Miami side on a six-game winning streak.

Both clubs have enjoyed strong starts to the 2025 MLS season with the Union leading the way in the East with four wins from five games, while the Herons sit in third on 10 points.

Javier Mascherano’s side should be refreshed after the international break as they prepare for an exacting schedule of upcoming matches, including a two-legged CONCACAF Champions Cup semifinal against Los Angeles FC.

The Herons head coach could keep Lionel Messi on the bench for Saturday’s game with an idea of starting the superstar, who missed Argentina’s recent World Cup qualifiers because of an adductor issue, in Los Angeles four days later.

Philadelphia coach Bradley Carnell will welcome back the MLS’s leading marksman Tai Baribo after international duty, and defender Olwethu Makhanya is available again after suspension.

Inter Miami vs. Philadelphia Union betting picks and predictions

Half Time Result - Draw (+160)

Inter Miami are the hot favorites to take another three points as they attempt to extend their win streak to seven games in all competitions.

The Herons did not play last weekend because it was their bye week. They would have been without Noah Allen, Benjamin Cremaschi, Santiago Morales and Telasco Segovia because of international call-ups.

There is a possibility that the interruption in the team’s schedule and the absence of that quartet from training could hurt the momentum Mascherano has created in early-season play.

The squad were in a good rhythm and coping well with the demands of a game every three or four days.

It may take some time for Inter Miami to click back into gear on Saturday, particularly as they are facing one of the better road teams in MLS.

The Union have won both of their away games in 2025, beating Orlando City 4-2 on their last visit to Florida and then defeating the lowly New England Revolution 2-0 in Foxborough.

However, both of those wins were secured with strong second-half displays as Carnell’s side could not grab the advantage before the interval.

Likewise, Inter Miami have been more of a potent force after half-time this season with three of their four MLS matches all square at the break. 

This clash is potentially a closer affair than the odds suggest because of Inter Miami’s upcoming schedule, so it may be worth backing the teams to be level after 45 minutes.

Over 2.5 Goals & Both Teams to Score - Yes (-125)

Seven of Inter Miami’s last eight MLS matches, dating back to last season’s MLS Cup Playoffs, have seen both teams score with Over 2.5 total goals.

The Herons have occasionally hit top gear in games this season only for a lapse in concentration to allow their opponents to score.

They have kept only two clean sheets in their last 15 MLS contests, but have scored in their last 35 consecutive games in all competitions.

The Philadelphia Union have shown they can get goals on the road, racking up six in their two away trips this season.

They also scored on their last visit to Chase Stadium, a 3-1 regular-season defeat last September.

Tai Baribo anytime goalscorer (+275)

Baribo has been a revelation for Philadelphia this season, scoring six goals in his first three games before drawing a blank in their one defeat to Nashville SC.

The Israeli international has picked up where he left off last season and has now bagged 15 goals in his last 24 MLS appearances.

Baribo has been getting great service from his teammates, but he deserves credit for finding the spaces in the penalty area to get his goals.

All six of them in 2025 have come from close range - either just inside or just outside the six-yard box - which indicates the 27-year-old has perfected the art of poaching.

He can make his mark against Inter Miami, who allowed Charlotte FC to attempt seven shots from inside the penalty area in their last home game.

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Inter Miami vs. Philadelphia Union odds

Inter Miami	-167
Tie	+350
Philadelphia Union	+375

Inter Miami vs. Philadelphia Union player props

Anytime Goalscorer

Lionel Messi (Inter Miami)	-120
Luis Suarez (Inter Miami)	+100
Leo Afonso (Inter Miami)	+175
Fabrice Picault (Inter Miami)	+200
Tadeo Allende (Inter Miami)	+200
Mikael Uhre (Philadelphia Union)	+260

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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.