The 2024/25 UEFA Champions League Round of 16 kicks off on Tuesday, and PSV will look to spring a surprise in the first leg when hosting Arsenal.
Both sides are dealing with injuries to key players.
PSV will likely be without prolific American attackers Ricardo Pepi and Malik Tillman. Pepi, who backs up club legend and captain Luuk de Jong, has been one of the most efficient forwards in the world since joining the Dutch side. Tillman is the club's joint-top scorer with three goals in the UEFA Champions League.
Arsenal, meanwhile, have been stuck playing central midfielder Mikel Merino as a striker because Kai Havertz, Gabriel Jesus, Gabriel Martinelli and Bukayo Saka are all out injured.
PSV vs. Arsenal will be streamed on Paramount+, which is the only way to watch the match with an English-language broadcast in the United States.
Fans based in the US can watch on TV via TUDN, which will have a Spanish-language broadcast.
PSV vs. Arsenal is scheduled to kick off at 3 PM ET/2 PM CT/ 12 PM PT on Tuesday, March 4 from PSV Stadion in Eindhoven, Netherlands.
PSV (4-3-3): Walter Benitez; Richard Ledezma, Ryan Flamingo, Olivier Boscagli, Mauro Junior; Joey Veerman, Ismail Saibari, Jerdy Schouten; Ivan Perisic, Luuk de Jong, Noa Lang
Arsenal (4-3-3): David Raya; Jurrien Timber, William Saliba, Gabriel, Riccardo Calafiori; Martin Odegaard, Thomas Partey, Declan Rice; Ethan Nwaneri, Mikel Merino, Leandro Trossard