Wide receivers D.J. Moore, Ja’Marr Chase, and Tyreek Hill all posted huge numbers to lead their teams to victory in Week 5.
There were some great games on this week's slate and a number of outstanding individual performances around the league. We’ve assessed all of the top players from Week 5 and explained why each one is noteworthy below.
8 receptions for 230 receiving yards, 3 TDs
DJ Moore played a starring role for the Bears in their 40-20 upset of the Washington Commanders on Thursday night, but there was little chance of him being knocked off this list when the Sunday games were played.
Not only did Moore help the beleaguered Bears to their first win for almost a year as they snapped a 14-game losing run, he did it in style with touchdown receptions of 20, 11 and 56 yards as part of a huge 230-yard day.
After winning their first game of the season, the Bears are out to +500 odds to have the worst regular-season record, behind the Panthers (+275) and Cardinals (+375).
26 carries for 136 rushing yards, 2 TDs & 4 receptions for 48 receiving yards
The Jacksonville Jaguars have looked right at home in London over the last two weeks, beating the Atlanta Falcons at Wembley last week before upsetting the Buffalo Bills at Tottenham Hotspur Stadium in Sunday's early game.
The Jaguars were the official road team for this contest but that wasn't a problem as running back Travis Etienne Jr. kept the chains moving with 184 rushing and receiving yards and two scores. The Jags improved to a 3-2 record and are +2500 odds to win the NFL Championship and -150 favorites to win the AFC South.
23 carries for 165 rushing yards & 2 TDs, 2 receptions for 30 receiving yards
Hundreds of fantasy football players will be cursing themselves for benching Zack Moss this week after top dog Jonathan Taylor was cleared to return for the Colts' Week 5 game against the Tennessee Titans.
Moss had done an outstanding job filling in for the injured starter and in fact that continued to be the case as Taylor had just six carries for 18 yards as he was eased gently back into action.
Moss shouldered the load again and had a career-high in rushing yards in the Colts' crucial 23-16 AFC South win. At 3-2, the Colts are now +200 to make the playoffs this season.
8 receptions for 181 receiving yards,1 TD
The Dolphins offense against the New York Giants' defense always looked like a potential mismatch and so it proved as rookie running back DeVon Achane, no stranger to this column, had 151 rushing yards and wide receiver Tyreek Hill was impossible to contain, showcasing his blistering speed.
Hill's fellow wideout Jaylen Waddle opened the scoring but Hill wowed the crowd with his 69-yard score at the start of the second half and ended up with 181 receiving yards in a 31-16 win.
The Dolphins are +1100 odds to win the NFL Championship and -130 to win the AFC East.
15 receptions for 192 receiving yards, 3 TDs
The Bengals offense had looked awful over the first four weeks of the season as QB Joe Burrow struggled to find his form after a calf injury, but they looked more like their old selves in a 34-20 win over the Arizona Cardinals.
Star wide receiver Ja'Marr Chase had complained of always being open and not getting the ball during their slow start, but he was fed early and often against the Cardinals. He connected with Burrow 15 times for 192 yards and three touchdowns.
The Bengals are +2500 odds to win the NFL Championship this season, while their AFC North odds are +350 and Chase is +2800 to be named the Offensive Player of the Year.
3 receptions for 67 receiving yards, 3 TDs
The unbeaten San Francisco 49ers delivered another performance to make the rest of the NFL sit up and take notice in a 42-10 win against the Dallas Cowboys.
Tight end George Kittle caught only four passes in the game, which might not sound too impressive, but 75% of them were touchdown catches. He posted the first two scores of the game from 19 and 38 yards and connected with unflappable QB Brock Purdy once again in the third quarter for his final score from 10 yards.
The 49ers are now the outright NFL Championship favorites at +450 odds, ahead of the Kansas City Chiefs at +550 and the Philadelphia Eagles at +600. They are +110 to win the overall #1 seed for the NFC playoffs and -105 odds to register over 13.5 regular-season wins.