2025 NBA Playoffs: New York Knicks vs. Boston Celtics second-round series odds

The New York Knicks are resounding -550 favorites to win the series against the Boston Celtics after winning Game 4 on Monday night, taking a 3-1 lead.

Jalen Brunson (39 points, 12 assists) put on a show in the second half as New York erased a 14-point deficit to win Game 4, 121-113, to get within one win of the franchise’s first conference finals appearance since 2000. Mikal Bridges, OG Anunoby and Karl-Anthony Towns each scored 20+ points in the victory.

But the story is all about Jayson Tatum, who suffered a non-contact right leg injury late in the fourth quarter and was taken to the locker room in a wheelchair. The Celtics superstar was putting on an all-time performance (42 points, 8 rebounds, 4 steals, 2 blocks) prior to going down.

It’s unlikely we see Tatum take the court again this series, or this season, which gives the Knicks a massive advantage in Wednesday’s Game 5.

Let’s take a look at the series odds following Monday’s madness.

New York Knicks vs. Boston Celtics second-round series odds

Knicks lead series 3-1

To Win Series - After Game 4

NY Knicks	-550
BOS Celtics	+400

Prior to the series, the Celtics were -750 favorites to win, with the Knicks +525 underdogs.

Series Correct Score - After Game 4

Series Score	Knicks to win	Celtics to win
4-1	+175	-
4-2	+150	-
4-3	+750	+400

Prior to the series, Celtics to win 4-1 (+190) and 4-0 (+330) were the outcomes with the shortest odds.

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Odds displayed within this article were correct at the time of writing and are subject to change.