The Philadelphia Eagles beat the Kansas City Chiefs 21-17 in a Week 11 rematch of last year's NFL Championship game.
It was Chiefs head coach Andy Reid's fourth-ever loss off a regular season bye week and his first such loss since 2017.
Last year, the Chiefs won 38-35 in Arizona to get their hands on the trophy, but they dropped to 7-3 after Monday's defeat. The Eagles are now 9-1 and leading the way in the NFC and the NFL.
When the schedule was announced earlier this year, eyes were immediately drawn to the Week 11 slate with the Chiefs hosting the Eagles.
In the recent NFL Championship, both teams traded blows from the start, scoring touchdowns on their opening drives, but on Monday, both offenses went three and out to begin the game on a wet night in Kansas.
Both quarterbacks took sacks on their respective opening drives, with the Eagles' Haason Reddick taking down Mahomes and the Chiefs' Trent McDuffie getting to Hurts.
Reid's Chiefs team learned their lessons from the opening drive, marching downfield to score their first touchdown as Mahomes found Justin Watson in the end zone.
Then Monday's game looked like it would turn into a repeat of the NFL Championship, as the Eagles did the same thing on the following drive when D'Andre Swift rushed for a touchdown to make it 7-7.
Hurts threw an interception to L'Jarius Sneed on the next Eagles possession after the scoring drive. On the ensuing drive, Mahomes marched the Chiefs downfield and threw an arced pass toward the end zone only for the Eagles trade deadline acquisition Kevin Byard to intercept it.
Hurts eventually did damage as he rushed for two touchdowns which both came in the second half.
The Eagles quarterback has had to battle a knee injury in recent weeks, but he looked pain-free, and although he helped his team get the job done, he believes the team can improve further.
He told reporters: "I don't think we played clean tonight. I don't think we played to our standard - nowhere near our standard.
"But I think the thing that you can't test or quantify is the resilience that a team has, the ability to persevere and see through things and overcome things, and this team has that.
"When you win games like we've won games, that builds a ton of character. We're kind of in, I guess, character development mode with the games we've played and how we've won. It can only serve us for great things in the future."
The Eagles have the best record in the NFL and they are available at +450 to win the Championship, the same price as the San Francisco 49ers and Chiefs.
Philadelphia coach Nick Sirianni had to juggle his offensive options, with tight end Dallas Goedert missing out on Monday with a forearm injury.
Goedert not only plays a huge part on the passing side of things, but the Eagles lean on him on the ground as an excellent blocker. However, the NFC leaders still found a way to have success without him.
Swift managed to pick up 76 yards from 12 carries, while Hurts added 29 rushing yards from the same amount of attempts.
Goedert's fractured forearm will sideline him for a few weeks, but if Monday's game is anything to go by, the Eagles can find a way collectively without him.
The Chiefs' 7-3 record is still likely to be enough to win the AFC West this season, while they could still be the No.1 seed in the AFC.
The Miami Dolphins, Baltimore Ravens, Cleveland Browns, and Jacksonville Jaguars will have something to say about that, but the Chiefs' defense will keep them competitive despite Monday's defeat.
However, their offensive struggles are not going away, and they will definitely need to improve in the off-season. Mahomes' only trustworthy option through the air is Travis Kelce and even he dropped a simple catch on Monday.
Through 10 games, Kansas has fallen short due to dropped passes, penalties and turnovers, and all of their weaknesses were on show in front of a home crowd.
Wide receiver Marquez Valdes-Scantling dropped a deep pass in the final few minutes which would have given the Chiefs the ball inside the Eagles five, and his error-prone season continues for now.
Watson also dropped a pass in the second half that would've put the Chiefs in prime field position.
Coach Reid will always find clever ways to get his team to win games, but the Chiefs will need to improve their pass attack if they want to retain their crown.