San Diego Padres vs. Houston Astros: Picks, Predictions, Odds, and Player Props

To close out this week in the MLB, we will be treated to an interleague game between the red-hot San Diego Padres and the Houston Astros.

This game between the Padres and Astros is set to take place on Sunday, April 20th at Minute Maid Park in Houston, Texas.

The expected first pitch time is 7:00 PM ET, and the game will be broadcast nationally on ESPN.

San Diego Padres vs. Houston Astros betting picks and predictions

San Diego Padres Money Line (+100)

Our best bet for this game will target the Padres to win. San Diego enters this game with a record of 15-6, the best record in the MLB.

The Padres are expected to start Dylan Cease, who has a record of 1-1 across four starts and has an ERA of 6.63.

Cease has made just one road start this season, against the Athletics, where he allowed nine earned runs over just 4.0 innings. However, he bounced back in his most recent start, allowing two earned runs against the Chicago Cubs at home.

As for the Astros, they enter this game with a record of 10-10 and are in fourth place in the American League West, trailing the first-placed Texas Rangers by 2.5 games.

Houston is set to counter with Framber Valdez, who has a record of 1-2 this season over four starts and an ERA of 4.91. In two home starts, he is 1-1 and has an ERA of 3.75.

Even though Cease had a terrible performance in his lone start on the road this season, he still looks to be the better pitcher to back.

San Diego is 10th in the MLB in scoring offense, averaging 4.57 runs per game, whereas Houston ranks 24th, averaging 3.75 runs per game.

The Padres failed to hang onto an early lead in Game Two of this series, however, they have a stronger offense and have been playing at a much more consistent level.

For that reason, backing the Padres to win (+100) will be our best bet.

Read more betting picks and predictions for the MLB on site.

San Diego Padres vs. Houston Astros odds

San Diego Padres	+100 ML
Houston Astros	-120 ML
Run Line	Padres +1.5 (-210) / Astros -1.5 (+175)
Total	Over 7.5 (-115) / Under 7.5 (-105)

San Diego Padres vs. Houston Astros player props

Player Home Run Odds

Manny Machado (San Diego Padres)	+425
Fernando Tatis Jr. (San Diego Padres)	+500
Luis Arraez (San Diego Padres)	+1550
Yordan Alvarez (Houston Astros)	+350
Christian Walker (Houston Astros)	+475
Jose Altuve (Houston Astros)	+800

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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.