New York Yankees vs. Los Angeles Angels: Picks, Predictions, Odds and Player Props

The first month of the 2025 MLB season has featured plenty of compelling contests, and the action continues on the diamond on Monday with an interleague matchup between the New York Yankees and Los Angeles Angels.

Fresh off a disappointing series against the Miami Marlins, the Angels currently sit in fourth place in the American League West, above only the Athletics, and things aren’t exactly looking up for a team that doesn’t expect to be contending for the postseason in 2025.

On the other side, New York sits atop the American League East standings at 32-20, with the Yankees having won eight of their last 10 games. New York is in a perfect position to take advantage of a soft spot within its schedule before things get a lot tougher with a series against the Dodgers to end the week.

Will the Yankees remain red-hot, or will the Angels find their way back into the win column? Let’s get into the odds, plus our expert’s betting picks and predictions for this contest.

New York Yankees vs. Los Angeles Angels betting picks and predictions

New York Yankees ML (-170)

The Yankees have established themselves as one of the best teams in baseball, and New York is in high gear after winning two out of three against the Colorado Rockies at Coors Field over the weekend, as most would have expected. 

The red-hot Aaron Judge and the rest of this New York lineup land in southern California on Monday looking to keep things going against right-hander Jack Kochanowicz, who has a very low strikeout rate of 14.8 percent, while posting a 47.4 percent hard-hit rate this season, according to Baseball Savant. 

Those numbers are certainly ominous for the Angels starter when looking across the diamond at the Bronx Bombers, as Judge and the other big bats are looking to tee off following a fairly muted performance at Coors Field on Sunday.

The Angels were rolling earlier this month, having won eight consecutive games from May 16-23. However, while Los Angeles was initially able to get back to .500, they lost a pair of games on Saturday and Sunday to the lowly Miami Marlins at home, while only scoring two runs of offense in those contests combined. 

Just when it looked like things were turning around for this embattled Angels franchise, they laid a big, fat egg. To make matters worse on Sunday, the winds in Anaheim were blowing out at a moderate pace to the left-center field power alley, which, if it continues, spells trouble against the likes of Judge and this New York lineup. 

This is an offense that won't need much help launching the ball against Kochanowicz and a very poor Angels bullpen, so let’s take New York on the money line as our best bet in this game. 

Over 9.5 Total Runs (-120)

This pitching matchup —Kochanowicz for the Angels and Ryan Yarbrough for the Yankees — is one that immediately indicates a high-scoring game, so it was a pleasant surprise that we’re actually getting a decent price on Over 9.5 at -120 for this contest.  

On paper, each lineup should be in position to succeed, with the Angels having averaged 6.4 runs per game over their last 10 contests, while the Yankees have averaged nearly five runs over their last 10 outings.

Not only are both starting pitchers pretty subpar from a metrics perspective, but both lineups profile well against each starter in terms of their splits and career history. 

Both starters could be in trouble early and often, and with each offense playing well entering this contest, this should aid the Over at Angel Stadium on Monday.

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New York Yankees vs. Los Angeles Angels odds

New York Yankees	-170 ML
Los Angeles Angels	+145 ML
Run Line	NY Yankees -1.5
Total	O/U 9.5

New York Yankees vs. Los Angeles Angels player props

Player Home Run Odds

Aaron Judge (NY Yankees)	+210
Trent Grisham (NY Yankees)	+375
Jasson Dominguez (NY Yankees)	+425
Logan O'Hoppe (LA Angels)	+450
Jorge Soler (LA Angels)	+450
Zach Neto (LA Angels)	+475

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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.