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Los Angeles Dodgers vs. San Diego Padres: Picks, Predictions, Odds and Player Props

The MLB played its first-ever game in South Korea on Wednesday, with the Los Angeles Dodgers beating the San Diego Padres 5-2 in Shohei Ohtani's first game as a Dodger.

The two teams face off again on Thursday in the second of this two-game series.

Los Angeles Dodgers vs. San Diego Padres betting picks and predictions

Shohei Ohtani Over 1.5 Total Bases (-115)

Ohtani signing with the Dodgers was the biggest move of the winter and arguably of recent years in the major leagues.

The two-way player and two-time American League MVP has moved across town from the Angels and to the National League favorites, the Dodgers.

Los Angeles are +170 to win the NL and just +375 to lift the World Series.

With all eyes on Ohtani in Seoul, he has already impressed with the bat in his first game in Dodgers blue.

With two hits and a crucial RBI in the four-run eighth inning, the sport’s superstar has already laid down a marker to LA’s rivals that he will be a big piece in their offense this season.

Los Angeles did pick up one lucky break in the first game as the Padres’ Jake Cronenworth saw a routine double play ball go straight through his glove, but the Dodgers had to take advantage of that fluke and did so.

Ohtani and their power-packed lineup looks set to be a major issue for teams all year and could have another big say in this matchup.

Yoshinobu Yamamoto Over 4.5 Strikeouts (-105)

The Los Angeles Dodgers went big this winter and alongside Ohtani signed star free agent pitcher and fellow Japanese pitcher Yoshinobu Yamamoto.

The starter signed a 10-year, $700 million contract in the offseason and will be looking to show his value immediately to his new ballclub.

Yamamoto had a 16-6 record with a 1.21 ERA last season with the Orix Buffaloes in Japan and looks set to impress despite an 8.38 ERA in three Cactus League outings.

Manager Dave Roberts made it clear that he expected his new star to sharpen up for this season opener and if he can translate some of his dominant record in Japan to the major leagues, he will be a huge success.

Between the new signing and the San Diego Padres’ Joe Musgrove, who posted a 3.05 ERA from 17 starts last year, this could be another pitchers' duel.

Under 8.5 (+100)

San Diego used seven of their 11 available pitchers in the first game between these two, so expect both teams to be happy to use their bullpen in this matchup.

The two teams won’t play another regular season game for a week after this clash, so will be happy to burn through their available pitching to keep things close with that in mind.

There were only seven runs scored in the game, five of which were earned and another pitcher’s battle could be on the cards in Seoul. 

Take the under 8.5 runs line here.

LA Dodgers Money Line -185

Despite San Diego starter Joe Musgrove’s impressive numbers last year, he has historically struggled against the Los Angeles Dodgers.

Musgrove is 0-7 with 32 runs and 24 walks given up in 59 2/3 innings over 11 career starts against the Dodgers.

That does not bode well for this game and it is hard to see past the loaded Los Angeles lineup having some more success against the San Diego starter.

With Yoshinobu Yamamoto expected to impress on the mound for the Dodgers, they look like a solid pick at on the money line to start the season with back-to-back wins and return to American soil having sent a warning to their rivals.

Read more betting picks and predictions for the MLB on site

Los Angeles Dodgers vs. San Diego Padres odds

LA Dodgers

-185 ML

SD Padres

+155 ML

Run Line

LAD -1.5 (+105)


O/U 8.5

Los Angeles Dodgers vs. San Diego Padres player props

Player Home Run Odds

Shohei Ohtani (LAD)


Max Muncy (LAD)


Mookie Betts (LAD)


Freddie Freeman (LAD)


Fernando Tatis Jr. (SD)


Manny Machado (SD)


Read Los Angeles Dodgers vs. San Diego Padres: How to watch, TV Channel, streaming, start time, starting pitchers, injury report and stats on site

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This article was written by a partner sports writer via Spotlight Sports Group. All odds displayed on this page were correct at the time of writing and are subject to withdrawal or change at any time.

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