Week 6 of the college football season is upon us and we're starting to get a true feel for which teams could really make some noise this season and potentially make the College Football Playoff.

There’s another great slate of matchups taking place this week and we’ve laid out the top college football Week 6 games to watch below.

No. 12 Oklahoma Sooners vs. No. 3 Texas Longhorns

The matchup of the weekend is without a doubt the Red River Rivalry taking place at noon ET.

Both the Sooners and Longhorns enter this matchup undefeated and, while Texas has seen more of the spotlight, the talent of this OU team cannot be ignored.

Their offense has already amassed 50+ points on three separate occasions this season.

As for the Longhorns, they’ve been one of the most consistent teams in all the nation to start this campaign. They already have a massive win over Alabama on their resume and a win here would solidify their CFP hopes for the time being.

Texas won last season’s meeting 49-0 and leads the series all-time with a record of 63-50-5, and they are favored on Saturday by -6.5.

No. 23 LSU Tigers vs. No. 21 Missouri Tigers

LSU enters this Week 6 slate as the only AP Top 25 team to have two losses on their schedule already, albeit to two other ranked teams in Florida State and Mississippi State.

Offensively the Tigers have been fine, but they’ve struggled to stop just about everyone on the defensive side of the ball. Three of their five opponents have scored at least 30 points, and two of them 45.

Missouri will be looking to stay perfect on the season as they’ve surpassed many preseason expectations for this squad already.

This matchup should be an exciting one, as three of Missouri’s five games have been decided by one possession. If they can hand Brian Kelly’s team another loss here, LSU fans may have a long rest of the season ahead of them.

LSU is favored by -5.5, while Mizzou is +190 ML.

No. 10 Notre Dame Fighting Irish vs. No. 25 Louisville Cardinals

After a heart-breaking loss to Ohio State, the Fighting Irish got back in the win column last weekend with a gritty victory at Duke.

While much of the talk centered around QB Sam Hartman to begin this campaign, it’s been the ND defense that’s been playing on another level. They’ve now gone three consecutive games allowing 17 points or less.

Head coach Jeff Brohm has come right in and made this Cardinals bunch not only competitive, but a good football team.

A perfect 5-0 in this campaign so far, Louisville gets its first taste of game action as an AP Top 25 team, having defeated NC State on the road last time out.

Notre Dame is favored by -6.5, while Louisville is +200 ML.

No. 20 Kentucky Wildcats vs. No. 1 Georgia Bulldogs

It’s not even basketball season and yet we’re seeing Kentucky as a ranked team. They’re certainly deserving of it, with a 5-0 record thus far.

Strength of schedule has played a role for sure, but last weekend’s win over a solid Florida team should put confidence in this group. They have maybe the toughest task of them all in Week 6, however.

That’s because they’ll be on the road trying to knock off the back-to-back defending champions in Georgia.

The Bulldogs surprisingly were in a 10-0 hole after the first quarter last week against Auburn, before eventually figuring things out to earn a 27-20 victory.

Georgia is still undefeated this season, but they look more vulnerable then they have in years past. The Bulldogs are favored by -14.5 and Kentucky are +450 ML.

No. 11 Alabama Crimson Tide vs. Texas A&M Aggies

Since falling to Texas and coupling that with a disappointing showing next time out against South Florida, the Crimson Tide have been absolutely rolling.

They beat a good Ole Miss team by two possessions and followed that up with a resounding 40-17 victory at Mississippi State in Week 5 and Jalen Milroe appears to have officially locked up the QB1 spot.

On the other side, the Aggies have played well in this campaign outside of their 15-point loss to Miami FL.

Beating good teams has been an issue for TAMU in recent seasons and they’ll need to be on their A-game to have any shot at upsetting ‘Bama.

Back-to-back wins against SEC opponents in Auburn and Arkansas the last two weeks should at least give A&M fans some hope, as should the fact that Alabama is favored by just -1.5.