Arizona Cardinals vs. Buffalo Bills: How to watch, TV channel, streaming, start time, injury report and stats

The Arizona Cardinals take a trip across the country to face the Buffalo Bills in Week 1 as highly-touted rookie WR Marvin Harrison Jr. makes his debut for the visitors.

MHJ projects to form a dangerous offensive duo with Cardinals QB Kyler Murray, who will hope to complete his first full NFL season since 2020. Murray came back from an ACL injury in the middle of last season and led Arizona to three of its four wins on the season.

The Bills have a new-look offense surrounding perennial MVP candidate QB Josh Allen. Allen has taken the Bills to the playoffs in each of the past five seasons, but the team has lost in the Divisional round in each of the past three seasons.

How to watch Arizona Cardinals vs. Buffalo Bills, TV channel and streaming

The Arizona Cardinals vs. Buffalo Bills game will be broadcast on CBS, which is available to watch through linear and cable TV and can be streamed through live TV streaming apps such as YouTubeTV or FuboTV.

Streaming will also be available on NFL+, which requires a paid subscription.

Arizona Cardinals vs. Buffalo Bills start time, date and venue

Arizona Cardinals vs. Buffalo Bills is scheduled to start at 1 PM ET/11 AM MT on Sunday, September 8 with the game taking place at Highmark Stadium in Orchard Park, New York.

Arizona Cardinals vs. Buffalo Bills injury report

Arizona Cardinals: WR Xavier Weaver - oblique, questionable; CB Darren Hall - hip, questionable; TE Tip Reiman - undisclosed, questionable; G Jon Gaines II - undisclosed, questionable; LB BJ Ojulari - knee, out; DE Darius Robinson - calf, out; OT Christian Jones - ankle, out; CB Elijah Jones - heel, out

Buffalo Bills: WR Curtis Samuel - toe, questionable; WR Marquez Valdes-Scantling - neck, questionable; S Baylon Spector - calf, questionable; S Damar Hamlin - hamstring, questionable; LB Nicholas Morrow - groin/core, questionable; DE Javon Solomon - calf, questionable; S Cole Bishop - shoulder, questionable; S Mike Edwards - hamstring, questionable; CB Taron Johnson - quad, probable; LB Matt Milano - biceps, out; OT Travis Clayton - shoulder, out

Arizona Cardinals vs. Buffalo Bills stats

• In eight games in 2023, Cardinals QB Kyler Murray completed 65.7 percent of his passes for 1,799 yards and a 10-5 TD-INT ratio while rushing 44 times for 244 yards and three TDs.
• Bills QB Josh Allen completed 66.5 percent of his passes for 4,306 yards and a 29-18 TD-INT ratio, leading his team to an 11-6 record while throwing the second-most interceptions in the NFL.
• The Bills finished 2023 ranked sixth in points scored per game with 26.5 and ranked fourth in points allowed with 18.3; the Cardinals were ranked 24th with 19.4 points scored per game and ranked 31st with 26.8 points allowed per game.
• Buffalo lost its two top receivers, Stefon Diggs and Gabe Davis, in the offseason and the team expects WRs Khalil Shakir, Curtis Samuel and rookie Keon Coleman to replace their production.
• Marvin Harrison Jr., who the Cardinals drafted fourth overall in the 2024 draft, caught 67 passes for 1,211 yards and 14 TDs last season at Ohio State.
• Arizona finished 30th out of 32 teams in sacks last season with 33; team sacks leader Dennis Gardeck finished the season with just 6.0.

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