May means we are entering the business end of the season across Europe and there are plenty of big games to get your teeth into from Spain, France and Germany this Tuesday.

In La Liga, Barcelona and Real Madrid are among the teams that will be in action, while in France, Champions League-chasing Lens will be on the road at Toulouse.

Arguably the game of the night will come in Germany, as Freiburg and RB Leipzig meet in the semi-finals of the DFB-Pokal.

Don't forget you can watch all the action across Europe's big leagues this midweek using bet365’s European Soccer Live Streaming Highlights.

Our four-fold acca takes in matches from all three countries and comes in at odds of almost 42/1.

Tuesday four-fold acca:

Barcelona to beat Osasuna to nil @ 4/5
Real Sociedad to beat Real Madrid @ 6/4
Toulouse v Lens - Draw @ 3/1
Freiburg to qualify against RB Leipzig @ 11/8

Odds were correct at time of writing and are subject to change.

La Liga glory to edge closer for Barca

What	Barcelona v Osasuna
Where	Camp Nou, Barcelona
When	18:30, Tuesday 2nd May
How to watch	bet365's European Soccer Live Streaming Highlights, Viaplay and LaLiga TV
Odds	Barcelona 2/9, Draw 5/1, Osasuna 14/1

It feels like a case of when and not if Barcelona will be crowned La Liga champions this season and they can take another giant step towards the title when they host an Osasuna side that are bound to have one eye on their upcoming Copa del Rey final.

Barca are unbeaten at home in the league this season, winning 13 of their 16 games to date, with much of their success being built on a phenomenal defensive record - they have conceded just twice on home soil in the league all term.

Real Madrid and Espanyol are the only sides to have left the Camp Nou having scored a La Liga goal and it is difficult to see a shot-shy Osasuna bucking that trend.

Jagoba Arrasate's side sit a respectable eighth in the standings, but they are averaging less than a goal-per-game in the league and have failed to net in three of their last six away assignments - the Barcelona win to nil certainly appeals at 4/5 in the Result/Both Teams to Score market.

Sociedad to add to Real's away-day blues

What	Real Sociedad v Real Madrid
Where	Anoeta Stadium, San Sebastian
When	21:00, Tuesday 2nd May
How to watch	bet365's European Soccer Live Streaming Highlights, Viaplay and LaLiga TV
Odds	Real Sociedad 6/4, Draw 12/5, Real Madrid 9/5

A Barcelona win would ramp up the pressure on Real Madrid ahead of their trip to Real Sociedad for Tuesday's late game and Los Blancos head into that fixture with patchy away form and perhaps their minds elsewhere.

Carlo Ancelotti's side have won just one of their last four away games in La Liga, most recently losing 4-2 at Girona and, with their title hopes already seemingly being over, they may take their eye off the ball further at the Anoeta.

Real have the Copa del Rey final and the first leg of their Champions League semi-final tie with Manchester City to come off the back of Tuesday's game, which means Ancelotti could also rotate his starting XI for the clash with Sociedad.

Champions League chasing Sociedad have won their last three matches at home and could prove to be the value option at 6/4 in the Full Time Result market.

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In-form duo to share the spoils

What	Toulouse v Lens
Where	Stadium de Toulouse, Toulouse
When	20:00, Tuesday 2nd May
How to watch	bet365's European Soccer Live Streaming Highlights and BT Sport 2
Odds	Toulouse 7/2, Draw 3/1, Lens 8/11

Two of Ligue 1's form sides will meet at the Stadium de Toulouse this midweek, as Toulouse play host to a Lens team that can move to within six points of the top of the standings with a victory.

Lens have certainly been the surprise package in France this year and they will head into this game having won five of their last six Ligue 1 matches.

However, wins have not always been forthcoming on the road for Franck Haise's side, as only Reims (nine) have drawn more away matches in the French top flight this term than Lens (eight).

With mid-table Toulouse also in form - winning four of their last five across all competitions - it is difficult to see either side losing on Tuesday, which makes the draw an intriguing option at 3/1 in the Full Time Result market.

Freiburg heading for Berlin

What	Freiburg v RB Leipzig
Where	Europa-Park Stadion, Freiburg
When	19:45, Tuesday 2nd May
How to watch	bet365's European Soccer Live Streaming Highlights
Odds	Freiburg 13/5, Draw 13/5, RB Leipzig 1/1

Freiburg and RB Leipzig will meet in the semi-finals of the DFB-Pokal on Tuesday and both sides will be hopeful of reaching the final after their respective victories over Bayern Munich and Borussia Dortmund in the previous round.

With just a place and two points separating the two sides in the Bundesliga table, this could prove a hard-fought contest, but home advantage should give Freiburg the advantage given they have only lost twice at the Europa-Park Stadion in the league all season.

Revenge could also be in the minds of Christian Streich's side, as Freiburg were beaten on penalties by Leipzig in the final of last season's DFB-Pokal, denying them what would have been a first major piece of silverware.

For their part, Leipzig have lost four of their last five away fixtures in all competitions, which further suggests Freiburg could have the edge, but there may be more value in backing the hosts To Qualify at 11/8 rather than to win the match inside 90 minutes.