There are two fixtures taking place on Tuesday in the Premier League, starting with Chelsea's clash against Bournemouth before Manchester United face Nottingham Forest at Old Trafford.
The World Cup break probably came at the right time for the Blues, who were struggling for form despite initial early promise in the reign of former Brighton boss Potter.
Chelsea have gone five games without victory in the top flight and come into this contest on the back of three straight losses across all competitions - failing to score in all of those defeats.
Nevertheless, Potter's troops will be expecting to defeat Bournemouth, who have lost four of their last five and are only three points above the relegation zone ahead of the domestic action returning.
Gary O'Neil takes charge as the permanent boss of the Cherries for the first time, following Bill Foley's American-led takeover of the club.
Elsewhere, Manchester United return to action in Tuesday's other game against Nottingham Forest, seeking to regain some consistency and keep up in the race for the top four.
The Red Devils face a Forest side who are beginning to get to grips with life back in the Premier League, following two wins in their last four league contests, but the Tricky Trees are still inside the bottom three.
Tuesday's first game comes from west London and Chelsea will be hoping for some Christmas cheer after a pretty dismal pre-World Cup autumnal period.
Graham Potter took over from Thomas Tuchel in early September and he was able to get some very positive results for the Blues early in his reign, taking them to an unbeaten run of 11 matches in all competitions.
However, against former club Brighton no less, Chelsea were thumped 4-1 and further losses against leaders Arsenal and top-four rivals Newcastle were to follow.
The main issue Potter has had is seeing his side score goals, with the Blues finding the back of the net only twice in their last five league contests where they have failed to win any of those.
Pierre-Emerick Aubameyang was brought in by Potter's predecessor Tuchel at the end of the summer transfer window but Kai Havertz is also under consideration for up top. There are also a plethora of attacking options to support those two players.
If anything, it is almost as if there are too many good players to choose from and their squad perhaps needs to be slimmed down.
Defensively, they have been okay under Potter but for the 4-1 thumping by Brighton and getting more out of their undoubtedly talented attacking line-up will be key going forward.
Bournemouth used the World Cup break to sort out the future of the club, with American Bill Foley completing his multi-million-pound takeover while O'Neil was named permanent successor to Scott Parker following three months in interim charge of the first team.
Foley, who owns NHL side Vegas Golden Knights, has spoken big on the club's future, saying he wants a state-of-the-art training ground and to make the club a stable Premier League outfit.
Despite their recent form, O'Neil probably did enough to warrant getting the job on a full-time basis and now the battle to stay up recommences.
The south-coast outfit were narrowly beaten 1-0 by Newcastle during the week in the EFL Cup and the boss admitted his squad had been hit by a virus in the camp, meaning some players may be absent for Tuesday's game.
Bournemouth lie 14th in the table and picking up anything from Stamford Bridge will be a bonus.
The big news emerging from Old Trafford over the World Cup break was the departure of Cristiano Ronaldo following his public criticism of the club and, more specifically, Erik ten Hag.
The writing had been on the wall for some time now and, in a move which suits all parties, the Portuguese superstar's deal was terminated to allow him to move onto pastures new.
Ten Hag will be relieved knowing that he no longer has to answer questions about Ronaldo and instead the Dutch tactician can focus on the rest of his squad.
His main challenge in the second half of the season will be to solve their inconsistent form which currently sees them lie fifth in the table. United have not managed to win back-to-back games in the league since their 3-1 win against Arsenal in early September.
Alejandro Garnacho's late winner saw them beat Fulham last time out in the top flight and they will be in an expectant mood against Forest, who haven't managed an away win in the league all season.
Steve Cooper's men looked like they could have been cast adrift of the pack following their early season form, so 18th position is probably a good return so far.
However, they need to solve their travel sickness issues if they are to stay in the division, though Wednesday's excellent 4-1 EFL Cup win at Championship high-flyers Blackburn should provide a springboard for them.