The group stages of Europe's club competitions are over and focus switches to Saturday's domestic action including a fascinating clash at the top of Serie A.
Napoli, flying in both the Champions League and the Italian top flight, are aiming to extend their lead with a victory at second-placed Atalanta while in Spain's Primera Liga, Barcelona legend Gerard Pique will retire after his side's home game against Almeria.
|What||Atalanta v Napoli|
|Where||Gewiss Stadium, Bergamo, Italy|
|When||17:00, Saturday 5th November|
|How to watch||BT Sport 1 & European Soccer Live Streaming Highlights|
|Odds||Atalanta 23/10, Draw , Napoli 23/20|
One of the games of the weekend in Europe sees Serie A leaders Napoli travel to second-placed Atalanta and the visitors are strong favourites to take three points.
Luciano Spalletti's league leaders have made a blistering start to the 2022/23 campaign so they won't have been too disheartened by Tuesday's 2-0 defeat at Liverpool on matchday six of the Champions League.
Napoli still topped Group A after winning their first five games, scoring 20 goals in the process, and their attacking quality should be too much for Atalanta.
Spalletti's men have scored 30 goals in 12 Serie A matches while Atalanta have notched only 18 times despite a soft set of early fixtures. Six of the Bergamo boys' eight wins came against teams in the bottom half and Napoli have already won away to champions AC Milan and highflying Roma and Lazio.
|What||TSG Hoffenheim v RB Leipzig|
|Where||Rhein-Neckar-Arena, Sinsheim, Germany|
|When||14:30, Saturday 5th November|
|How to watch||European Soccer Live Streaming Highlights|
|Odds||Hoffenheim 19/10, Draw 11/4, RB Leipzig 5/4|
RB Leipzig are 5/4 to continue their impressive form under new manager Marco Rose with a Bundesliga victory away to shots Hoffenheim.
Leipzig have swaggered into the Champions League last 16 after winning their last four group games, including a 3-2 home victory over European champions Real Madrid and this week's 4-0 win at Shakhtar Donetsk.
Germany forward Timo Werner suffered an injury early on against Shakhtar and will miss the World Cup but Leipzig have plenty of in-form attacking players who can help them extend their hot streak.
Christopher Nkunku, the Bundesliga's player of the year in 2021/22, has scored in each of his last four appearances for Leipzig and, having notched in the 10th, 32nd and 18th minutes of his last three games, he looks a tempting first-goalscorer bet at .
|What||Barcelona v Almeria|
|Where||Camp Nou, Barcelona, Spain|
|When||20:00, Saturday 5th November|
|How to watch||LaLigaTV & European Soccer Live Streaming Highlights|
|Odds||Barcelona 1/8, Draw , Almeria 14/1|
It may only be Barcelona's 13th fixture of the Primera Liga campaign but it will be the end of an era at Camp Nou on Saturday as centre-back Gerard Pique is set to retire after the clash with Almeria.
Pique should enjoy a winning send-off as Barca are 1/8 to beat their visitors, who have drawn two and lost 13 of their 15 meetings with the Catalan giants.
Despite the sentiment surrounding Pique's retirement, Barca must remain focused as they are one point behind rivals Real Madrid in the title race with both sides winning 10 of their first 12 games.
Pique, a World Cup and European Championship winner with Spain, has made almost 400 league appearances for Barca during a stellar career. He is 4/1 to score at any time on his final outing at Camp Nou and to be the last goalscorer.
|What||Angers v Lens|
|Where||Raymond Kopa Stadium, Angers, France|
|When||20:00, Saturday 5th November|
|How to watch||BT Sport 5 & European Soccer Live Streaming Highlights|
|Odds||Angers 17/4, Lens 4/6, Draw|
Ligue 1's bottom club Angers are 17/4 to snap a five-match losing streak on Saturday but they face a tough test against visitors Lens.
Angers conceded two second-half goals to lose 2-0 at Monaco last weekend but they had been trailing at half-time in their previous four league defeats and Lens are 5/4 to be ahead at the break.
Lens goalkeeper Brice Samba helped Nottingham Forest win promotion to the Premier League last season and he has enjoyed his move to Ligue 1 as part of a defensive unit who have conceded only one goal, a penalty from Lille's Jonathan David, in their last seven matches.