St Kilda veteran Dan Hannebery has suffered more bad luck on the injury front and is facing a spell on the sidelines after suffering a calf injury.
St Kilda are priced at 28/1 to win the 2022 AFL grand final and will need Hannebery fit and out on the pitch to boost their chances.
The 31-year-old midfielder has had a nightmare on the injury front over the last three seasons and has been restricted to eight games or less in each campaign.
Hannebery would have been hoping his issues were behind him going into the new season but the injury jinx has struck again.
Hannebery suffered the calf injury during a training session on Saturday and at this stage St Kilda are unable to put a time-frame on his recovery.
St Kilda football boss David Rath admits it is a big setback but they will stand by the player to do all they can to get him fit and healthy again.
"This is clearly a disappointing start to the 2022 season for Dan," Rath said. "Given his recent history with soft tissue injuries,
Dan has been working closely with the high performance and medical team to slowly build his load and he had been making some promising steps towards a return.
"While this isn't ideal, we know Dan will approach this next phase of rehabilitation with complete professionalism.
"Our medical team are working through those next steps with Dan, but our primary focus at this moment is on supporting him through this."