There's a full Premier League card this weekend with title challengers Arsenal and Manchester City featuring among the seven games taking place on Saturday.

We've sifted through the seven-match card and come up with a four-fold which works out at around 49/1.

The acca features bets from the 15:00 kick-offs at Arsenal, Aston Villa and Brighton and is capped by the evening's live showdown between midweek FA Cup flops Southampton and Leicester City.

Saturday four-fold acca:

Our Premier League four-fold selection are priced up at 49/1.

Leicester to win at Southampton @ 8/5
Arsenal v Bournemouth - Arsenal HT/FT @ 8/11
Aston Villa v Crystal Palace - FT Draw @ 23/10
West Ham v Brighton - Draw no bet @ 12/5
Odds were correct at time of writing and are subject to change

Foxes can pile the misery on sorry Saints

What	Southampton v Leicester City
Where	St Mary's, Southampton
When	17:30, Saturday 4th March
How to watch	Sky Sports Main Event & Premier League
Odds	Southampton 7/4, Draw 23/10, Leicester 8/5

Two clubs wallowing in the misery of dismal FA Cup exits meet at St Mary's where Leicester City can kick Southampton while they are very, very down.

The visitors have at least had an extra 24 hours to get over their fifth-round home defeat by Blackburn Rovers, a result that hardly registered on the Richter scale of upsets compared to Grimsby Town going to St Mary's and duffing up a woeful Saints side.

Ruben Selles will naturally make changes galore, but the fact is this sorry Saints outfit are a poor side, starved of confidence and absolutely mistake-riddled at the back.

Leicester have lost three in a row after winning three in a row, though two of those setbacks were at Manchester United and at home to Arsenal, and they played well against the Gunners.

Saints haven't won any of their last five home games against Leicester, a sequence that includes that never-to-be-forgotten 9-0 dismantling in 2019. James Maddison scored the eighth that night and should be fit to help Leicester land the 8/5 against a dispirited opponent.

Cherries' top-four toils spell Emirates danger

What	Arsenal v Bournemouth
Where	Emirates Stadium, London
When	15:00, Saturday 4th March
Odds	Arsenal 1/5, Draw 6/1, Bournemouth 12/1

Bournemouth have trailed at the break and gone on to lose the match ten times already in the Premier League this season and Arsenal can make that 11.

It's 8/11 the Arsenal - Arsenal Half Time/Full Time bet, what looks a fairly safe option and preferable to the 1/5 the hosts over 90 minutes.

Certainly the bet copped when the Gunners visited the Vitality Stadium in August, when Martin Odegaard's brace put the league leaders 2-0 in front inside 11 minutes. They went on to win 3-0.

Bournemouth are arguably sturdier than they were back then, though their record against the current top four isn't encouraging if you're contemplating siding with the Cherries somehow - it reads played five, lost five, with 17 goals shipped.

Mikel Arteta's visitors come into the game with spirits sky-high after making it three wins in a row on Wednesday night with a comprehensive 4-0 dismantling of Everton.

The Cherries have scored only four goals in their last nine top-flight outings and know their future won't be determined by fixtures like this one.

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Palace set to share spoils once more

What	Aston Villa v Crystal Palace
Where	Villa Park, Birmingham
When	15:00, Saturday 4th March
Odds	Aston Villa 21/20, Draw 23/10, Crystal Palace 14/5

Draw masters Crystal Palace are on a stalemate streak at the moment which suggests they can eke out another point against Aston Villa at Villa Park as they inch towards safety.

A lack of wins is not helping Palace's quest for mid-table security, but a barrage of draws is at least keeping their noses above water.

The most recent of those was on Saturday night when they more than deserved a 0-0 draw at home to Liverpool, a match they arguably should have won.

That made it five draws in six for Patrick Vieira's Eagles, illustrating how nicely organised the Frenchman has got his side, but how abjectly short of decent strikers they are.

The return of Wilf Zaha from a hamstring injury cannot come soon enough for Vieira, though whether it's in time for this match remains to be seen.

Villa, FA Cup humiliation by Stevenage notwithstanding, are vastly improved under Unai Emery and were delighted with last weekend's 2-0 win at Everton which ended a three-game losing run and saw Ollie Watkins score in a fifth successive match.

Watkins is 7/4 to score at any time, 4/1 to score first, though in what could well be a low scorer the 23/10 for the draw appeals more.

Hammers can avoid Amex defeat

What	Brighton v West Ham
Where	Amex Stadium, Brighton
When	15:00, Saturday 4th March
Odds	Brighton 4/5, Draw 13/5, West Ham 7/2

West Ham haven't won an away game in the Premier League since August, but that doesn't mean they are necessarily awful travellers and the Hammers can avoid defeat at Brighton.

Yes, David Moyes' men have gone ten without a road success in the top-flight, but it's a list of narrow defeats and draws which hardly hints at a crisis on their travels.

Indeed, they have also won five away games in Europe and the FA Cup and fancied they would make that six on Wednesday when they went 1-0 up at Manchester United only to fall apart late on.

But they are playing well enough to believe they can get something from Brighton, who were beaten 1-0 at home by Fulham the last time they set foot on their home turf.

Matches between these sides have historically been tight - six of the last eight ended in draws - and it's worth noting that while there may be eight places between them they share an identical defensive record.