If the Tampa Bay Buccaneers go all the way again, Tom Brady will be firmly in the mix to win a sixth Super Bowl MVP award.
But at this early stage of the playoffs, and with 14 teams still dreaming of Super Bowl LVII glory, there are quite a few players with better prospects of earning the prestigious accolade.
It is nearly three years since Mahomes won his first Super Bowl MVP award and, at the time, few thought it would be his last.
The sixth-year quarterback also appears to be relatively injury free after shrugging off a recent hand injury to throw eight touchdowns and just one interception over the final four weeks of the regular season.
Last year, he threw 11 TDs and three picks in the postseason with an average QB rating of 118, and rates the obvious favorite to scoop the award.
Allen has had a mixed season, but proved that he is capable of stepping up to the plate when his team needs him most in last season's playoffs.
If the Bills are to fulfill their destiny and win Super Bowl LVII in what has been an incredibly difficult year for them, Allen is the player most likely to top the MVP vote.
Hurts sustained an injury and missed two consecutive games late in the year which have impacted his regular season MVP chances.
He ended the season with 3,701 passing yards, 22 touchdowns, and only six interceptions and, of all the quarterbacks on this list, he is the most likely to take the MVP award any which way his team takes the title.
He may not be quite up there with Mahomes for clutch, playmaking ability, but he isn't too far behind and has arguably the best set of wide receivers to target of any playoff QB.
The Hollywood scriptwriters will be rooting for the rookie to keep his team on track for Super Bowl glory and he would be a popular choice in MVP voting because of his Cinderella story.
Prescott has improved his fumble rate and has taken fewer sacks than most other leading quarterbacks this season, but he has the highest interception rate of any playoff-bound triggerman.
Seven running backs have earned MVP honors, but the last was Terrell Davis in 1998. No player has rushed for more than 125 yards in the Super Bowl this century and no one has surpassed 110 yards in the past 10 years.
All of which suggests it is becoming tougher for RBs to shine in the big game. Logically, teams with defenses that cannot stop the run simply don't make it to the big game and often rushers are so banged-up by the end of the campaign they are running out of juice.
McCaffrey will be a key player for the 49ers in the postseason, but they have such an array of star names on either side of the ball that he may struggle to sparkle if San Francisco take the title in either a shoot-out or defensive masterclass.
Bosa, however, may have a better chance of being recognized if the Niners win ugly by shutting their opponents down and just doing enough on offense to win the Lombardi Trophy.
Von Miller was the last defensive player to be named MVP after he recorded six tackles, 2.5 sacks, two forced fumbles, and two quarterback hurries in Super Bowl 50 and defensive end Bosa is not beyond making that level of impact.