The Chicago White Sox right-handed pitcher Lance Lynn will miss Opening Day after suffering a slightly torn right knee tendon and will undergo surgery on Tuesday.
Lynn will have four weeks of rehab followed by four weeks of ramping up to pitching again it was announced by White Sox General Manager Rick Hahn.
The White Sox are 12/1 to win the World Series, however Lynn exited his spring training start on Saturday with right knee discomfort.
The 34-year -old limped off the field after a pitch in the fourth inning against the Arizona Diamondbacks.
Lynn struggled with right knee inflammation last season and went on the injured list for 10 days.
He also spent nearly a month after the season ended resting and rehabbing his knee. Lynn went 11-6 with a 2.69 ERA in 28 starts last season.
Speaking to the official Chicago White Sox website, Hahn said: "Manager Tony La Russa will have some clarity tomorrow as to what order we'll have the guys.
"Obviously it's unfortunate that we have to spend this first several weeks without Lance.
"It's not anything that will likely be unique to us in terms of the unique season we have ahead of usand it's an opportunity for some of the other arms we'll be carrying with the expanded roster to fill some of that void."
MLB announced last week that in April, rosters will be expanded from 26 to 28.
News of Lynn's injury comes after the White Sox recently announced reliever Garrett Crochet will require Tommy John surgery and will miss the entire 2022 season.