A Casemiro-less Manchester United travel to the Emirates, looking to bounce back from their disappointing draw with Crystal Palace, against title challengers Arsenal.
Michael Olise's last-minute free-kick halted Manchester United's nine-match winning run in all competitions, putting a dent in any title aspirations Erik ten Hag's men may have, and the suspension to Casemiro leaves United with a major hole to plug in midfield.
Meanwhile Arsenal strengthened their title credentials with an impressive win over Tottenham to go favourites for the title for the first time this season, and another win will further bolster their ambitions for a first league title since 2004.
Steve Freeth has a Bet Builder for Sunday evening's clash.