Brazil have confirmed that Gabriel Jesus will play no further part in the World Cup after withdrawing from the tournament with a knee injury.
The striker started Friday's 1-0 defeat to Cameroon but limped off in the second half. The Selecao have now confirmed he and defender Alex Telles will miss the rest of the tournament and are due to undergo scans to assess the extent of their setbacks.
Brazil remain the 11/5 favourites To Win Outright in Qatar but have been left without a player with the potential to feature heavily as an impact substitute in the knockout rounds.
What: World Cup
Where: Qatar
When: Sunday 20th November - Sunday 18th December
How to watch: BBC and ITV
Odds: Brazil 11/5, Argentina 5/1, France 11/2, Spain 6/1, England 9/1
Qatar was supposed to be a shot at redemption for Jesus, who failed to score four years ago in Russia and has admitted that the experience left him "scarred".
However, Tite's preference for Richarlison, despite Jesus' superior club form, has left the Gunners star waiting for his chance.
He had played just 38 minutes before Friday's game and he struggled against Cameroon as the much-changed Selecao failed to gel.
After substitute appearances against Serbia and Switzerland, the 25-year-old came off after 64 minutes against the Idominatable Lions with a suspected knee injury.
He will undergo scans to assess the damage but he has now been ruled out of the rest of the World Cup, with Brazil 3/10 Full Time Result for their last 16 assignment on Monday against South Korea.
Jesus scored the last time the pair met, a 5-1 friendly win for Brazil in June, but Tite will now have to look elsewhere for attacking alternatives to Richarlison after Saturday's news.
Pedro, who replaced Jesus on Friday, might not be his go-to alternative, although Vinicius Junior and Rodrygo could also offer something through the middle.
Mikel Arteta and his Arsenal staff will now be waiting anxiously as they continue planning towards the resumption of the Premier League on Boxing Day.
The Gunners sit five points clear of Manchester City and get back down to business with a London derby at home to West Ham. They are 4/9 Full Time Result to collect a 10th straight Premier League home win, a run that stretches back to last April.
Jesus may not have scored since the 3-1 win over Tottenham on 1st October, but his impact on the Gunners since joining from Manchester City has been sizeable.
The former Palmeiras striker has also provided five assists and his commitment to defending from the front has helped Arsenal keep a joint-Premier League best of seven clean sheets.
Of course, there is every chance that Jesus' departure from Qatar is purely a precaution and the scans could come back suggesting all that is required is rest.
That would be a huge boost for Arsenal, who are 10/11 To Win a Major Trophy this season and have three to play for.
They kick off their FA Cup campaign away to League One Oxford on 9th January and are 7/1 in that competition To Win Outright, in the process lifting the trophy for a record-extending 15th time.
Arsenal are also into the last 16 of the Europa League and are 4/1 To Win Outright ahead of 9/2 Barcelona and 8/1 Manchester United.
However, their primary goal is a first Premier League title since the Invincibles of 2003/04, currently priced at 9/4 To Win Outright.
Arteta will be desperate to have Jesus fit for January, with the Londoners facing a tough time of it with fixtures against Newcastle on the 3rd, Tottenham on the 15th and Manchester United on the 22nd.
Saturday's news about Jesus is a significant blow for Brazil but it could be an even bigger issue for Arsenal.
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