The contest will mark WBC champion Fury's first outing in the ring since knocking out fellow Brit Dillian Whyte with a devastating uppercut at Wembley in April.
His opponent Derek Chisora has been in competitive action as recently as July, defeating Bulgarian veteran Kubrat Pulev via split decision at the London O2 Arena.
The upcoming bout has proved unpopular amongst boxing fans, with Chisora representing an underwhelming alternative opponent for champion Fury after talks collapsed to finally set up a super-fight with long-standing rival .
Having already comfortably defeated Chisora on two occasions, there are fears amongst fight fans that the upcoming contest will not be a competitive spectacle.
The heavyweight trilogy between Tyson Fury and Derek Chisora will take place on Saturday 3rd December 2022.
The fight will take place at the Tottenham Hotspur Stadium in London.
It will be the second boxing match to be hosted at the £1bn 62,850-seater stadium, after Anthony Joshua's first defeat to Ukrainian Oleksandr Usyk in September 2021.
The fight will be shown live on BT Sport Box Office priced at £26.95.
World heavyweight champion Tyson Fury has been priced as a huge 1/20 favourite for the fight, with odds of 9/1 for a victory for opponent Derek Chisora. For Fury to win by way of KO, TKO or Disqualification you can get odds of 4/11.
The full undercard has been confirmed as follows:
Tyson Fury vs Derek Chisora - WBC heavyweight title
Daniel Dubois vs Kevin Lerena - WBA 'Regular' heavyweight title
Yvan Mendy vs Denys Berinchyk
Karol Itauma vs Vladimir Belujsky
Isaac Lowe vs Sandeep Singh Bhatti
Royston Barney Smith vs Cruz Perez
The current holder of the WBC and The Ring magazine heavyweight titles, Tyson Fury is a fighter with an undefeated professional record of 32-0-1.
A total of 23 of Fury's 32 victories have come by way of knockout, with the draw on his record coming in his first meeting with American Deontay Wilder in an iconic clash in Los Angeles in 2018.
Fury first became world champion after defeating Wladimir Klitschko in Dusseldorf via unanimous decision back in 2015.
The Gypsy King has met upcoming opponent Derek Chisora twice before, winning on points in 2011 before forcing 'Del Boy' to retire in the 10th round of their second bout in 2014.
38-year-old Derek Chisora has a professional boxing record of 33-12-0, with a total of 23 of his victories arriving by knockout.
Chisora's most impressive wins on his resume could be argued to have come against Danny Willliams, Carlos Takam and David Price.
The Zimbabwe-born fighter has come undone twice to his upcoming opponent Tyson Fury, however, losing on points in 2011 before retiring in the 10th round of their second meeting in 2014.