Wigan Warriors have one hand on the League Leaders' Shield and a victory over Leeds Rhinos and a Hull KR loss to Leigh Leopards would see the reigning champions finish top of the pile for the second season running.
The Warriors beat Rovers on home soil last week but another tough test awaits them on Friday with fast-finishing Leeds still in the hunt for a play-off place with two rounds of the regular season remaining.
The Rhinos have been rejuvenated under new head coach Brad Arthur, winning four of their last five matches, and that sequence includes a stunning 30-4 victory over Wigan at Headingley last month.
This Super League Round 26 fixture is live on Sky Sports+ in the UK.
The match kicks off at 20:00 BST on Friday 13th September and will be played at the DW Stadium in Wigan.
Leeds have won four of their last six league meetings with Wigan.
The Rhinos won 30-4 when these two sides last met in August.
Wigan winger Liam Marshall has bagged 24 tries this season.
Leeds are looking for their fourth straight Super League victory.
Wigan Warriors wins | 45 |
Draws | 4 |
Leeds Rhinos wins | 35 |
*Stats relate to Super League results
Read the latest tips, predictions and odds for Wigan Warriors v Leeds Rhinos.
Matt Peet has a virtually full strength squad to choose from with Harry Smith and Liam Farrell retaining their places after returning to the side last week against Hull KR.
Willie Isa is back in training but is likely to miss out.
Mikolaj Oledzki returned after a four-game absence in the win over Hull FC last week and should keep his place in the side.
Mickael Goudemand was the man to make way but will be pushing for a recall this week.