Newcastle will be looking for League Cup revenge against Manchester United when the two clash on Sunday, while there is also a big relegation clash at the London Stadium. 

The Magpies lost to the Red Devils at Wembley at the end of February, prolonging the north-east outfit's wait for a first piece of silverware since 1969, but Eddie Howe's men will be hoping they can make up for that result when they welcome Erik ten Hag's side to St James' Park. 

Before that 16:30 clash on Tyneside, there is a massive game at the other end of the Premier League table as West Ham and Southampton, who are both in the bottom three, clash at the London Stadium in the 14:00 kick-off.

Saints to provide tough challenge

What	West Ham v Southampton
Where	London Stadium, London
When	14:00, Sunday 2nd April
How to watch	Sky Sports Main Event & Premier League
Odds	West Ham 8/11, Draw 13/5, Southampton 4/1

While Southampton may be rooted to the bottom of the table, they are still within touching distance of the sides outside of the relegation zone and they will be eyeing a huge three points at fellow strugglers West Ham. 

The Hammers are only a point ahead of Sunday's visitors but they did hit a bit of form before the international break, with a 1-1 draw against Aston Villa coming in between two victories over AEK Larnaca in the Europa Conference League. 

West Ham are also unbeaten in their last five matches at home across all competitions, so they have proven to be a tough nut to crack at the London Stadium, but the Saints do arrive off the back of some promising results themselves. 

Signs of improvement under Selles

Southampton's league form last month made for decent reading, with a 1-0 victory over Leicester City followed by a 0-0 draw against Manchester United, a 2-0 loss to Brentford and then a thrilling 3-3 draw with Tottenham. 

On the road, the Saints have put in some positive displays of late, with a 1-0 win at Chelsea and the stalemate at Old Trafford coming either side of a narrow 1-0 loss at Leeds and another case of under 1.5 goals is 8/1. 

The pressures of playing in front of a packed St Mary's has potentially proven too much for Ruben Selles' side, but they look better on the road and should give West Ham some problems. 

Draw or Southampton at 21/20 in the Double Chance market is worthy of consideration. 

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Home form key for Magpies

What	Newcastle v Manchester United
Where	St James' Park, Newcastle
When	16:30, Sunday 2nd April
How to watch	Sky Sports Main Event & Premier League
Odds	Newcastle 13/10, Draw 12/5, Man Utd 2/1

After suffering three straight defeats across all competitions, which included the 2-0 League Cup final loss to the Red Devils, Newcastle have recorded back-to-back 2-1 wins over Wolves and Nottingham Forest to boost their chances of a top-four finish. 

The Magpies are currently fifth in the standings but they know a victory against United on Sunday would see them jump into third, leapfrogging Spurs and Erik ten Hag's troops. 

Eddie Howe has an almost fully fit squad to choose from for this clash, with Miguel Almiron and Anthony Gordon the only two notable absentees in an attacking sense, but the same can't be said of the Red Devils, who are without the suspended Casemiro. 

Rashford wait for Man Utd

Although Ten Hag has "good hope" Marcus Rashford, 21/10 in the Anytime Goalscorer market, will play after he was forced to withdraw from England's squad due to an unspecific knock, there are still doubts over his fitness and being without the forward would be a huge blow.

Man Utd are also taking on a Newcastle side that has lost just one of their 17 assignments across all competitions on Tyneside and the vociferous home crowd will be hoping to spur their team onto a crucial victory against a United side that have been stuttering on their travels. 

Ten Hag's men have won just one of their last four away league matches - against relegation-threatened Leeds - while they were thumped 7-0 by Liverpool in their last top-flight fixture on the road. 

A home win for Newcastle could be considered at 13/10, with another 2-1 Correct Score of 9/1 holding value. 

Much could depend on Rashford's fitness, while United colleague Bruno Fernandes, 10/3 in the anytime goalscorer market, is always dangerous in an advanced midfield position.