Ahead of what's set to be a fascinating battle for the 2025 MotoGP World Championship, check out the latest outright winner odds.
(Odds will display when market is available)
The first rider with a satellite team to be crowned champion since Valentino Rossi in 2001, Jorge Martin heads into the new campaign embarking on a new chapter with Aprilia.
With the added pressure of attempting to defend his crown, Martin also possesses the extremely difficult challenge of fighting against the two factory Ducati riders, Francesco Bagnaia and Marc Marquez.
Equipped with the best bike on the grid, two-time victor Bagnaia and six-time champion Marquez are expected to contest for race victories with the ultimate goal of adding another title to their illustrious collections.
Marquez was riding with Gresini last year on board a GP23 which propelled him back to the front of the grid and revitalised a career which had been on the decline following a spate of injuries.
Back to his breathtaking best, the Spaniard will be looking to make a seamless transition at Ducati and get the jump on his new teammate, Bagnaia.
The immensely talented Pedro Acosta will aim to build on his collection of podiums during last year's impressive debut campaign by fighting for a maiden race win, although his title prospects are likely to be hindered by the limitations of his KTM.