Top of the table Manchester City make the short journey over to Old Trafford where they meet rivals Manchester United.
The Citizens -- for the first time since 2016 -- will be without Pep Guardiola in the dugout for a Manchester Derby after the Spaniard called time on his storied tenure in charge at City after the conclusion of last season.
Enzo Maresca has picked up where Guardiola left off thus far, winning all three of his Premier League matches in charge, as well as overseeing a perfect start to their UEFA Champions League campaign.
United also applied themselves well in Europe in the week with a emphatic 4-0 win over UCL newcomers Sabah, but their domestic efforts haven't been as fruitful. They responded well to opening day defeat to Hull by demolishing Ipswich on home soil, however, their inability to hold onto a lead late on against Everton will have incensed manager Michael Carrick.
Steve Freeth is hoping that a member of City's defence can make his presence known a little further up the pitch...
Manchester United v Manchester City Prediction
Best Bet: Josko Gvardiol to have 1+ Shot on Target @ 11/4
"That late goal at Everton will have really hurt Manchester United and it's noticeable again that they are giving up big chances from set plays. Branthwaite had two, Tarkowski had one and Hull scored from two set plays, of course, in that opener. There's only really Harry Maguire that offers that aerial presence, that dominance, in both boxes actually.
"Josko Gvardiol -- a big favourite of mine -- can play centre-back or left-back, but he's been playing left-back this season. He's a threat from a dead-ball situation, as we know, and from open play as well he scored against Bournemouth this season.
"Gvardiol has averaged over one shot per game in the last few seasons during his career at Manchester City and, as I mentioned earlier, Leif Davies managed to find room at the back post at Old Trafford, I can see him [Gvardiol] getting into the box also and profiting from that.
"There is a tiny, tenuous link that he scored in this fixture two years ago, actually from a corner on that occasion, but he is dangerous advancing into the box; which is why I'm going to go for Gvardiol to have 1+ Shot on Target at 11/4."
Key Match Stats
Manchester City have won their opening three Premier League matches this season
Erling Haaland has scored eight goals in 10 matches against Manchester United
United have netted 11 times in their last three games
Read more football betting tips and predictions on site.
Get the latest tips from the Football Betting Club on their YouTube channel.
All odds displayed on this page were correct at the time of recording and are subject to withdrawal or change at any time.
