Manchester City have been priced up at 200/1 to win the Quadruple in 2025/26.
After a first trophyless campaign since Pep Guardiola's first season, it would be a remarkable turnaround to win all four major trophies this time around, but City will welcome back Rodri, who was a huge absence last term.
bet365's Steve Freeth said: "It remains to be seen whether the early departure from the Club World Cup will prove to be a blessing in disguise, and if the Rodri injury is nothing more than a minor knock because Manchester City clearly missed the Ballon d’Or winner last season.
"Pep Guardiola’s side find themselves in the unusual position of second favourites for the Premier League title, but with a fit Rodri, along with the new faces settling in, we could see Manchester City launch a familiar assault on silverware.
"It would be foolish to write them off."
After failing to win a trophy in his first season in the Premier League, Guardiola guided the Citizens to a 100-point campaign 12 months later, winning a domestic treble the season after.
It would be unwise to dismiss City's ambitions too quickly; they've spent nearly £300m in 2025 alone to add to their bounty of options all over the pitch, with Tijjani Reijnders, Rayan Cherki and Rayan Ait-Nouri all joining over the summer.
City will have to cope without the legendary Kevin De Bruyne, however. The brilliant Belgian struggled with injuries in his latter years at the Etihad, but when fit he remained the Premier League's finest playmaker, striking up a potent partnership with Erling Haaland.
Haaland will also benefit from the return of Rodri as City regain control of games - though their shock defeat to Al Hilal suggests there's work to do in that department. Haaland has scored 83 goals in 96 games playing with Rodri, with Cherki tasked with replacing De Bruyne as the team's primary creator.
Phil Foden was also a reason behind City's struggles; after a superb 2023/24 season in which Foden won the PFA Player of the Year, Premier League Player of the Year and the FWA Footballer of the Year, Foden was restricted to just 20 Premier League starts, contributing to just nine goals, significantly down on the 27 from the season before, and Guardiola will hope to have the 25-year-old fit and firing against next season.
Their remarkable squad depth means they'll be a danger in both domestic cups. They were beaten finalists in the FA Cup last term and a heavily rotated side was knocked out of the EFL Cup by a strong Tottenham side in North London.
The Premier League looks to be a three-horse race with Liverpool strengthening through Florian Wirtz, Jeremie Frimpong and Milos Kerkez with a winger and a forward still being targeted, while Arsenal are a reliable goalscorer away from being a real threat.
The UEFA Champions League looks as competitive as it has for a number of years, with Liverpool, Real Madrid, Barcelona, Arsenal, Paris Saint-Germain and City all backable at single-figure prices.