With Manchester United gearing up for what will likely be another trying campaign, we take a look at the latest odds for the Red Devils to be relegated from the Premier League.
(Odds will display when market is available).
bet365's Sports and Trading expert Steve Freeth said: "There was always going to be one loser from the high-stakes game and for a club like Manchester United the consequences could be catastrophic.
"Transfer targets earmarked if they had gained UEFA Champions League qualification are likely to be discarded as the Red Devils may need to look further down their list of targets and possibly need to sell.
"Although they are 16/1 and not among the favourites to be relegated, there could be a knock-on effect. The losing mentality from their Premier League campaign at the end of this season, combined with this chastening defeat, may be hard to shift for a while."
Manchester United were most recently relegated in 1974, just six years after winning the European Cup. As their squad aged, with their star players not adequately replaced, combined with the retirement of Sir Matt Busby, the club fell down the table, being relegated at the end of the 1973/74 season.
Although it's widely recalled that a goal scored by United legend Denis Law - then playing for Manchester City - sealed their fate, results elsewhere meant United were already relegated.
Manchester United have also been relegated from the top flight in 1894, 1922, 1931 and 1937.
Any odds displayed were correct at the time of writing and are subject to fluctuation.