After beating Reading on Saturday, National League North side Kidderminster Harriers will host Premier League West Ham United in the fourth round of the FA Cup.
Russell Penn's side produced the shock of the third round to give themselves the chance of a plum draw, and they were rewarded with a meeting against David Moyes' men.
The Hammers advanced into the fourth round thanks to Sunday's 2-0 success over Leeds United and will fancy their chances of reaching the fifth round when they travel to Aggborough Stadium between 4th-7th February, with a number of games set to available through bet365's Sports Live Streaming.
Thomas Tuchel's Chelsea have been far from their best of late, but a place in the fifth round of the FA Cup should be theirs after they were handed a home draw against League One Plymouth.
The Blues beat Chesterfield 5-1 on Saturday evening and the European champions will be desperate to move closer to this year's final, having lost 1-0 to Leicester at Wembley in May.
Fellow Premier League side Crystal Palace have also been given a home tie, with League Two Hartlepool United set to travel to the capital after they came back from behind to beat Blackpool 2-1.
Southampton will welcome Coventry City to St Mary's as the Saints look to celebrate their recent takeover with a historic cup run.
There was the potential for four all-Premier League ties in this year's fourth round, with the pick of the games potentially taking place at the Emirates Stadium.
However, just like they did in 2018, Nottingham Forest knocked out Arsenal and will now host Leicester City, with the defending champions forced to play without the injured Jamie Vardy for the first few rounds of the competition.
Wolves extended their unbeaten run to six matches in all competitions by beating Sheffield United 3-0 on Sunday and their reward is another home draw against fellow Premier League side Norwich City.
Tottenham left it late after going 1-0 down against Morecambe, but Antonio Conte's troops will now face Brighton in London thanks to a 3-1 win courtesy of goals from Harry Winks, Lucas Moura and Harry Kane.
Everton and Brentford will square off at Goodison Park, which could be a challenging game for the Toffees, as Bees coach Thomas Frank has already expressed his desire to take the competition seriously.
Liverpool looked to be on their way out of the competition in the third round after going 1-0 down against Shrewsbury. Jurgen Klopp was forced to turn to the club's best youth products due to injuries, but it was the experienced duo of Roberto Firmino and Fabinho that helped them over the line as they scored during a 4-1 success.
The Reds, who last won the competition in 2006, will entertain Cardiff City at Anfield in a repeat of the 2012 League Cup final.
Reigning Premier League champions, Manchester City, were also drawn at home, and they will face Marco Silva's Fulham at the Etihad Stadium.
Manchester United, 4/6 to win, welcome Aston Villa to Old Trafford on Monday evening in the final tie of the third round and the winner will go on to face Championship outfit Middlesbrough.
Bournemouth, who also play their football in the second tier, welcome National League Boreham Wood to the south coast while there is an all-Yorkshire tie on the cards as Huddersfield Town entertain Barnsley.
Another all-Championship affair sees Queens Park Rangers travel to Peterborough United, while League One Cambridge United's reward for beating Newcastle is a home fixture against Luton Town.
2013 winners Wigan Athletic are focused on their League One fortunes but are still in the FA Cup and head to Stoke in the fourth round.