Co-hosts Canada have made it through the group stage at a World Cup for the very first time and take on South Africa in LA.
Jesse Marsch's men have won, lost and drawn at the tournament so far, finishing runner-up behind Switzerland in Group B.
They take on a South Africa side that head into this game as underdogs following their exploits in the group as they too harbour hopes of making the last 16 for the very first time in their history.
How to watch South Africa v Canada, live stream and TV channel
South Africa v Canada will be available to watch live in the UK on either BBC One or ITV.
Eligible customers in the UK, Ireland, Greece, Netherlands and Australia will also be able to bet on and watch the World Cup at bet365.
South Africa v Canada kick-off time, date and venue
South Africa v Canada will be played at the Los Angeles Stadium, California and kick-off time is set for 20:00 BST.
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