The New Saints won 3-0 away against FK Panevezys in Lithuania and the pair renews hostilities in the Conference League on Thursday.
After being knocked out of the UEFA Champions League and UEFA Europa League, TNS are 90 minutes away from qualifying for a European competition beyond August for the first time, with the winner going through to the new-look league phase.
The match has not been selected for TV coverage in the UK but the match will be broadcast on streaming platform SolidSport.
The New Saints v FK Panevezys will kick off at 18:30 on Thursday 29th August at Park Hall Stadium, Oswestry.
Last Thursday's meeting was the pair's first competitive fixture and The New Saints ran out the 3-0 winners at the Vilniaus LFF Stadionas.
The score was 0-0 at half-time before Daniel James Davies, Daniel Williams and Ben Clark netted after the break to put Craig Harrison's team within touching distance of qualifying for a UEFA competition proper for the first time.
Thursday's hosts had the weekend off, but Panevezys were in action, drawing 1-1 away to Dainava on Sunday.
The New Saints wins | 1 |
Draws | 0 |
FK Panevezys wins | 0 |
*H2H stats refer to all competitions
The weekend break means The New Saints may name the same side that started in Vilnius, although Clark could come into the line-up as a reward for his goal after replacing Rory Holden with 80 minutes gone.
Forward Jordan Williams is still suspended following his red card against Petrocub.
Stijn Vreven made two changes at Dainava, with Nicolas Gorobsov and Federico Palacios being replaced by Jovan Cadjenovic and Domantas Vaicekauskas.
Both are expected to return to the starting side in Oswestry.