Host nation USA kicked off their Copa America bid with a 2-0 win over Bolivia and know a victory on Thursday would see them qualify for the next round with a game to spare.
Opponents Panama meanwhile went down 3-1 to Uruguay and defeat could see them eliminated if Marcelo Bielsa's men avoid defeat against Bolivia.
How to watch Panama v United States and TV channel
Panama v USA is available to watch live on bet365's Live Sports Streaming service.
The match will also be broadcast on Premier Sports 1 in the UK.
Panama v United States kick-off time, date and venue
Panama v United States will be played at the Mercedes-Benz Stadium in Atlanta, Georgia, and kick-off is at 23:00 BST on Thursday 27th June 2024.
Panama v United States stats and head-to-head record
Panama claimed a famous victory over USA in the semi-finals of the Gold Cup in July last year, prevailing on penalties after a goalless 90 minutes and a 1-1 scoreline after extra time. However, they have lost four of their last six games and so their form heading into this crucial encounter does not bode well.
The United States have won five of the last seven meetings between these two nations, while the Stars and Stripes have just one defeat in normal time across their last 13 competitive fixtures.
Panama v United States head-to-head record
Panama wins | 4 |
Draws | 4 |
United States wins | 18 |
Read the latest tips, predictions and odds for Panama v United States
Panama v United States team news
Panama team news
Panama came through their opener against Uruguay unscathed but boss Thomas Christiansen could opt to make a few changes.
Minnesota midfielder Carlos Harvey was a surprise omission against Uruguay and could make an appearance against USA, as one of three players in the Los Canaleros squad who play their club football in MLS.
United States team news
United States have a clean bill of health following their win over Bolivia. Weston McKennie was booked against the South Americans but should keep his starting spot and boss Gregg Berhalter may opt to continue with the same first XI.
You can use our betting hub to see the latest Copa America betting odds and much more.
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