Having failed to win on the opening weekend, both Napoli and Bologna will look to lay down a marker when they meet on Sunday in Serie A.
Antonio Conte's first game in charge of Napoli did not go to plan, as they lost 3-0 to Verona on their travels.
Bologna are also under new management, with Vincenzo Italiano now at the helm, and his side secured a 1-1 draw against Udinese on the opening weekend.
Napoli v Bologna will be shown live on bet365's Sports Live Streaming service.
The match will also be broadcast live on TNT Sports 1 in the UK.
Napoli v Bologna will start at 19:45 BST on Sunday 25th August, and will take place at Stadio Diego Armando Maradona, Naples, Italy.
Napoli were stunned by Verona last weekend, and they are winless in eight in Serie A after a terrible end to the 2023-24 campaign.
Bologna's 1-1 draw against Udinese was their fourth successive draw at home in Serie A, while they ended last season with one defeat in nine on the road.
The two teams last met in May, with Bologna running out 2-0 winners in Naples.
Bologna wins | 48 |
Draws | 42 |
Napoli wins | 60 |
*H2H stats refer to all competitions
Striker Victor Osimhen has yet to take part in training for Napoli as he eyes a move away, so Giacomo Raspadori, Giovanni Simeone and Walid Cheddira will compete to start up front.
Alessandro Buongiorno and David Neres, both recent recruits for Napoli, are set to start on the bench.
Italiano will have to decide who to start up front, with Santiago Castro hoping to keep new signing Thijs Dallinga out of the team.
Emil Holm will hope to make his belated debut, but fellow summer recruit Nicolo Cambiaghi will miss out with a serious knee injury, and he joins Lewis Ferguson and Oussama El Azzouzi on the sidelines.