Manchester United enter the EFL Cup at the third-round stage on Tuesday, with League One Barnsley hoping to pull off a cup upset on their travels.
The Red Devils moved up to 10th in the Premier League after their 3-0 win over Southampton, while the Tykes are seventh in League One after collecting 10 points from their first six matches.
Manchester United v Barnsley will be available to watch in the UK on Sky Sports Main Event and Sky Sports Football.
Manchester United v Barnsley is scheduled to start at 20:00 BST on Tuesday 17th September and will take place at Old Trafford, Manchester, England.
After losing their last two games before the international break, the Red Devils returned to winning ways at St Mary's.
Erik ten Hag's troops ran out 3-0 victors to win their second league game of the campaign.
Barnsley fell to a 3-0 loss to Stevenage on Saturday, which was their first defeat in four in all competitions.
The two sides last met in the EFL Cup in 2009, with United running out 2-0 winners on that occasion.
Manchester United wins | 4 |
Draws | 1 |
Barnsley wins | 1 |
*H2H stats refer to all competitions.
Ten Hag is expected to make several changes to his team in order to give his fringe players some vital minutes.
Matthijs de Ligt, Lisandro Martinez and Noussair Mazraoui were all substituted against Saints, although the latter was only suffering from cramp.
Harry Maguire and Jonny Evans are likely to fill in for De Ligt and Martinez, while Manuel Ugarte will hope to make his full debut after stepping off the bench at the weekend.
Darrell Clarke will be without Conor Hourihane for this clash, but Max Watters and Fabio Jaio should be available after returning from injury from the bench against Stevenage.